Cosmotil 500 mg+125 mg (Tablet)

Unit Price: ৳ 50.00 (2 x 4: ৳ 400.00)
Strip Price: ৳ 200.00

Medicine Details

Title

  • Cosmotil 500 mg Tablet

Categories

  • Antibiotics
  • Medicine
  • Pharmaceuticals

DosageForm

  • Tablet

DosageStrength

  • 500 mg

Indications

  • Pharyngitis/Tonsillitis caused by Streptococcus pyogenes
  • Acute Bacterial Otitis Media caused by Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis
  • Acute bacterial maxillary sinusitis caused by Streptococcus pneumoniae or Haemophilus influenzae
  • Lower respiratory tract infections including pneumoniae caused by Streptococcus pneumoniae, Haemophilus influenzae, Klebsiella spp., Staphylococcus aureus
  • Uncomplicated skin and skin-structure infections caused by Staphylococcus aureus or Streptococcus pyogenes
  • Uncomplicated urinary tract infections caused by E.coli or Klebsiella pneumoniae
  • Bone and Joint Infections caused by Staphylococcus aureus
  • Uncomplicated Gonorrhoea caused by Neisseria gonorrhoeae
  • Early Lyme Disease (erythema migrans) caused by Borrelia burgdorferi
  • Septicemia caused by Staphylococcus aureus, Streptococcus pneumoniae, E.coli, Haemophilus influenzae & Klebsiella spp.
  • Switch therapy (Injectable to oral)

Pharmacology

  • Bactericidal activity against a wide range of Gram-positive and Gram-negative susceptible organisms
  • Inhibition of bacterial cell wall synthesis by interfering with the transpeptidation process

DosageAndAdministration

  • 250 mg b.i.d. for Pharyngitis/Tonsillitis for 5-10 days
  • 250 mg b.i.d. for Acute bacterial maxillary sinusitis for 10 days
  • 250-500 mg b.i.d. for Acute bacterial exacerbation of chronic bronchitis for 10 days

Interaction

  • Concomitant administration of probenecid with Cefuroxime-Clavulanic Acid increases the area under the serum concentration versus time curve by 50%

Contraindications

  • Known allergy to cephalosporin
  • Pseudomembranous Colitis

SideEffects

  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal discomfort or pain
  • Renal dysfunction (<0.2%)
  • Anaphylaxis (<0.2%)
  • Angioedema (<0.2%)

PregnancyAndLactation

  • Use with caution in the first trimester
  • Can be safely used in later pregnancy to treat urinary and other infections
  • Excreted into breast milk in small quantities

PrecautionsAndWarnings

  • Given with care to patients receiving concurrent treatment with potent diuretics
  • Caution in patients with history of colitis

TherapeuticClass

  • Second generation Cephalosporins

StorageConditions

  • Store in a cool, dry place (below 30°C), away from light and moisture

UsageFAQs

  • Indicated for the treatment of infections caused by sensitive bacteria
  • Starts working within 2-3 hours after taking it
  • Effects last for an average duration of 4-8 hours
  • No habit-forming tendencies reported
  • Safe to consume alcohol in moderation
  • Quick tips for usage and side effects

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