S-Fenac TR 50 mg (Capsule (Timed Release))
Unit Price: ৳ 1.20 (100's pack: ৳ 120.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Diclofenac sodium |
| Company | Seema pharmaceuticals ltd |
| Also available as |
Indications
- Rheumatology
- Inflammatory and degenerative forms of rheumatism
- Chronic involutive
- Polyarthritis
- Ankylosing spondylarthritis
- Osteoarthritis
- Spondylarthroses
- Acute gout
- Peri-articular rheumatic disorders
- Surgery and Traumatology
- Sprain
- Bruises
- Dislocations
- Fractures
- Soft tissue injuries
- Surgical interventions
- Obstetrics and Gynecology
- Primary dysmenorrhoea
- Episiotomy
- Adnexitis
- Endometritis
- Parametritis
- Salpingitis
- Mastitis
- Otorhinolaryngology
- Pre-operative medication for the prevention of pain
- Inflammation
- Swelling
- Dentistry
- Post-operative and post-traumatic pain
- Inflammation
- Swelling
- Urogenital tract
- Renal and biliary colic prevention
- Treatment of inflammation and swelling
Pharmacology
- Potent non-steroidal anti-inflammatory drug (NSAID)
- Anti-rheumatic
- Analgesic
- Antipyretic properties
- Uricosuric effect
- Inhibits prostaglandin biosynthesis
- Rapid and complete absorption from the gastro-intestinal tract
- Metabolized in the liver
Dosage & Administration
- Adult dosage: 75-150 mg daily in 2-3 divided doses
- Dose reduction in long term use
- Children dosage: 1-3 mg of diclofenac/kg body wt. daily in divided doses
- Lowest effective dosage recommended for elderly patients
- External use dosage: 2-4 g of Diclofenac gel applied to the skin 3-4 times daily
Interaction
- May increase plasma concentrations of lithium and digoxin
- Risk of haemorrhage with the combined use of diclofenac and anticoagulants
- Can be given together with oral antidiabetic agents
- Nephrotoxicity reported in patients receiving cyclosporine and diclofenac concomitantly
- Serious toxicity reported when methotrexate and NSAIDs given within 24 hours of each other
- Convulsions may occur due to an interaction between quinolones and NSAIDs
Contraindications
- Hypersensitivity to any ingredient
- Peptic ulcer
- Hypersensitivity to Diclofenac or other non-steroid anti-inflammatory agents
- Contra-indicated in asthmatic patients
Side Effects
- Generally well tolerated
- Mild, rare, and transient adverse effects
- Epigastric pain
- Eructation
- Nausea
- Diarrhea
- Dizziness
- Headache
- Peripheral edema
- Skin reactions such as rash and eczema
Pregnancy & Lactation
- Employed only for compelling reasons during pregnancy
- Lowest effective dose to be used
- Not recommended during the first trimester of pregnancy
- Not recommended during lactation
Precautions & Warnings
- Close observation in rare instances of peptic ulceration or gastrointestinal bleeding
- Advanced age patients should be kept under close observation
- Avoid contact with eyes or mucus membranes
- Avoid ingestion
Therapeutic Class
- Drugs for Osteoarthritis
- Drugs used for Rheumatoid Arthritis
- Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
- Store in a cool and dry place
- Protected from light
- Store below 30°C
- Keep out of the reach of children