Krimizole 200 mg/5 ml (Oral Suspension)
10 ml bottle: ৳ 15.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Mystic pharmaceuticals ltd |
| Also available as |
Indications
- Single and mixed infestations of hookworm, roundworm, threadworm, whipworm, strongyloides, tapeworm, opisthorchi, hydatid
Description
- Benzimidazole anthelmintic
- Active against most nematodes and some cestodes
- Vermicidal, ovicidal, and larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Blocks glucose uptake in helminths
- Depletes energy level leading to immobilization
- Extensively metabolized, especially in the liver
- Poorly absorbed from the gastrointestinal tract
- Metabolite albendazole sulphoxide has anthelmintic activity
Dosage & Administration
- Recommended doses for adults and children
- Different doses for different parasitic infections
- Specific dosages for hydatid disease based on patient weight
- Duration and repetition of treatment for certain conditions
Interaction
- No reported pharmacodynamic or pharmacokinetic interactions
Contraindications
- Not recommended for neonates
- Reduced dose may be needed for children under 10kg
- Not to be used in pregnancy or lactation
- No evidence of dose alteration needed in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Reversible alopecia
- Rash
- Fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsion and meningism in cerebral disease
Pregnancy & Lactation
- FDA Pregnancy category C
- Avoided in pregnancy and lactation unless benefits outweigh risks
Precautions & Warnings
- Blood counts and liver function tests before and during treatment
- Caution with breastfeeding
- Pregnancy exclusion before treatment
- Constant medical supervision with regular monitoring in Echinococcosis treatment
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in dry place
- Away from light and heat
- Keep out of the reach of children