Atasin 80 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Atorvastatin calcium |
| Company | Aci limited |
| Also available as |
Title
Atasin 80 mg Tablet
Categories
- Medicine
- Health
- Cholesterol Management
Description
Atasin 80 mg Tablet is a selective inhibitor of HMG-CoA reductase. It is used to reduce elevated cholesterol and triglycerides levels, prevent heart attacks, and treat conditions such as hypercholesterolaemia and dyslipidemia.
DosageAndAdministration
- Recommended starting dose for adults is 10 or 20 mg once daily, can be increased to 80 mg once daily if necessary
- For children (10-18 years), the initial dose is 10 mg once daily, may be increased to a max of 20 mg once daily
Pharmacology
- Absorption: Rapidly absorbed after oral administration, with maximum plasma concentrations occurring within 1 to 2 hours
- Distribution: 98% bound to plasma proteins, extensive distribution in the body
- Metabolism: Extensively metabolized to active derivatives, primarily metabolized by cytochrome P450 3A4
- Excretion: Eliminated primarily in bile, mean plasma elimination half-life is approximately 14 hours in humans
Interaction
- Antacid: Coadministration may decrease plasma concentrations of atorvastatin
- Colestipol: Coadministration may decrease plasma concentrations but increase LDL-C reduction
- Digoxin: Plasma digoxin concentrations may increase by approximately 20% with coadministration
- Erythromycin: Plasma concentrations of atorvastatin may increase approximately 40% with coadministration
Contraindications
Should not be used in patients with hypersensitivity to any component, active liver disease, unexplained elevations of serum transaminases, or history of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors
SideEffects
- Constipation
- Flatulence
- Dyspepsia
- Abdominal pain
- Infection
- Headache
PrecautionsAndWarnings
Liver function tests should be performed before initiation of treatment and periodically thereafter. Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected.
StorageConditions
Keep in a dry place away from light and heat, out of the reach of children
ChemicalStructure
- MolecularFormula: C33H35FN2O5
- StructuralFormulaUrl: https://medex.com.bd/storage/res/g-res-92-atorvastatin-calcium-chemical-structure-vKDE8RIA4syu8MLTgdLW.svg
CommonQuestions
- What is Atasin 80 mg Tablet used for?
- How should I take Atasin 80 mg Tablet?
- What are the uses of Atasin 80 mg Tablet?
- What are the side effects of Atasin 80 mg Tablet?
- What are the storage instructions for Atasin 80 mg Tablet?
PregnancyAndLactationSafety
- Pregnancy: Contraindicated during pregnancy, safety in pregnant women not established, should be suspended for the duration of pregnancy
- Lactation: Not known whether it is excreted in human milk, contraindicated during breastfeeding
SpecialPopulations
- Geriatric: Plasma concentrations are higher in healthy elderly subjects than in young adults
- Pediatric: Pharmacokinetic data in the pediatric population are not available
- Gender: No clinically significant difference in LDL-C reduction between men and women
OverdoseEffects
Specific treatment is not available for atorvastatin overdose, liver function tests should be performed and serum CK levels monitored