Restonix 0.5 mg (Tablet)
Unit Price: ৳ 5.00 (50's pack: ৳ 250.00)
Medicine Details
| Category | Details |
|---|---|
| Generic | Clonazepam |
| Company | The white horse pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of panic disorder with or without agoraphobia
- Treatment of Lennox-Gastaut Syndrome (petit mal variant)
- Treatment of akinetic and myoclonic seizures
- Adjunct in the treatment of absence seizures (petit mal)
- Long-term use effectiveness not systematically studied
Pharmacology
- Exhibits anticonvulsive effects
- Exhibits sedative effects
- Exhibits muscle relaxing effects
- Exhibits anxiolytic effects
- Enhances GABAergic neurotransmission
- Modulates GABA receptor affinity for neurotransmitter
- Suppresses paroxysmal activity in epilepsy
Dosage & Administration
- Initial dose for adults with seizure disorders
- Incremental dosage adjustments
- Maximum recommended daily dose
- Initial dose for adults with panic disorder
- Initial dose for pediatric patients
- Dosage based on body weight
Interaction
- No alteration of phenytoin pharmacokinetics
- No alteration of carbamazepine pharmacokinetics
- No alteration of phenobarbital pharmacokinetics
- Effect on the metabolism of other drugs not investigated
Contraindications
- Hypersensitivity to benzodiazepines
- Clinical or biochemical evidence of significant liver disease
- Acute narrow angle glaucoma
Side Effects
- CNS depression
- Drowsiness
- Ataxia
- Behavior problems
- Abnormal eye movements
- Aphonia
- Coma
- Tremor
- Vertigo
- Depression
- Amnesia
- Hallucinations
- Increased libido
- Insomnia
- Psychosis
- Palpitations
Pregnancy & Lactation
- Potential teratogenic effects
- Observations on anticonvulsant drugs as teratogens
- Importance of weighing benefits against risks
- Administration only if compelling indication
- Recommendation to discontinue breastfeeding
Precautions & Warnings
- Potential increase in generalized tonic-clonic seizures
- Potential absence status with valproic acid
- Increased pharmacologic effects in geriatric patients
- No dose adjustment required in renal impairment
- Potential alteration in hepatic impairment
Use in Special Populations
- Increased production of saliva and bronchial secretion in infants and small children
- Greater pharmacologic effects in geriatric patients
- No dose adjustment required in renal impairment
- Potential alteration in hepatic impairment
Overdose Effects
- Common symptoms
- Life-threatening possibilities
- Respiratory depressant effects
- Enhanced effects with other CNS depressants
- Recommended monitoring, supportive measures and treatment
Therapeutic Class
- Adjunct anti-epileptic drugs
- Benzodiazepine hypnotics
Reconstitution
- Requirements for slow intravenous injection
- Dilution with water for injection
- Preparation before administration
- Dilution for intravenous infusion
- Stability and storage conditions for infusions
- Use of intramuscular injection in exceptional cases
Storage Conditions
- Dry place away from light and heat
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C15H10ClN3O3
- Representation of Chemical Structure
Commonly Asked Questions
- Usage as a sleeping pill
- Recommendation for duration of usage
- Withdrawal symptoms after cessation
- Monitoring of suicidal thoughts and actions
- Possible weight gain
- Impact on memory
- Consequences of overdose
- Avoidance of specific medication combinations
- Quick Tips for safe usage