Restonix 0.5 mg (Tablet)

Unit Price: ৳ 5.00 (50's pack: ৳ 250.00)

Medicine Details

Category	Details
Generic	Clonazepam
Company	The white horse pharmaceuticals ltd
Also available as	Restonix 2 mg tablet

Indications

Treatment of panic disorder with or without agoraphobia
Treatment of Lennox-Gastaut Syndrome (petit mal variant)
Treatment of akinetic and myoclonic seizures
Adjunct in the treatment of absence seizures (petit mal)
Long-term use effectiveness not systematically studied

Pharmacology

Exhibits anticonvulsive effects
Exhibits sedative effects
Exhibits muscle relaxing effects
Exhibits anxiolytic effects
Enhances GABAergic neurotransmission
Modulates GABA receptor affinity for neurotransmitter
Suppresses paroxysmal activity in epilepsy

Dosage & Administration

Initial dose for adults with seizure disorders
Incremental dosage adjustments
Maximum recommended daily dose
Initial dose for adults with panic disorder
Initial dose for pediatric patients
Dosage based on body weight

Interaction

No alteration of phenytoin pharmacokinetics
No alteration of carbamazepine pharmacokinetics
No alteration of phenobarbital pharmacokinetics
Effect on the metabolism of other drugs not investigated

Contraindications

Hypersensitivity to benzodiazepines
Clinical or biochemical evidence of significant liver disease
Acute narrow angle glaucoma

Side Effects

CNS depression
Drowsiness
Ataxia
Behavior problems
Abnormal eye movements
Aphonia
Coma
Tremor
Vertigo
Depression
Amnesia
Hallucinations
Increased libido
Insomnia
Psychosis
Palpitations

Pregnancy & Lactation

Potential teratogenic effects
Observations on anticonvulsant drugs as teratogens
Importance of weighing benefits against risks
Administration only if compelling indication
Recommendation to discontinue breastfeeding

Precautions & Warnings

Potential increase in generalized tonic-clonic seizures
Potential absence status with valproic acid
Increased pharmacologic effects in geriatric patients
No dose adjustment required in renal impairment
Potential alteration in hepatic impairment

Use in Special Populations

Increased production of saliva and bronchial secretion in infants and small children
Greater pharmacologic effects in geriatric patients
No dose adjustment required in renal impairment
Potential alteration in hepatic impairment

Overdose Effects

Common symptoms
Life-threatening possibilities
Respiratory depressant effects
Enhanced effects with other CNS depressants
Recommended monitoring, supportive measures and treatment

Therapeutic Class

Adjunct anti-epileptic drugs
Benzodiazepine hypnotics

Reconstitution

Requirements for slow intravenous injection
Dilution with water for injection
Preparation before administration
Dilution for intravenous infusion
Stability and storage conditions for infusions
Use of intramuscular injection in exceptional cases

Storage Conditions

Dry place away from light and heat
Keep out of the reach of children

Chemical Structure

Molecular Formula: C15H10ClN3O3
Representation of Chemical Structure

Commonly Asked Questions

Usage as a sleeping pill
Recommendation for duration of usage
Withdrawal symptoms after cessation
Monitoring of suicidal thoughts and actions
Possible weight gain
Impact on memory
Consequences of overdose
Avoidance of specific medication combinations
Quick Tips for safe usage

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