Cardual 5 mg+10 mg (Tablet)
Unit Price: ৳ 11.07 (3 x 10: ৳ 332.10)
Strip Price: ৳ 110.70
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atorvastatin |
| Company | Aci limited |
Title
- Amlodipine and Atorvastatin Tablet
Categories
- Hypertension Medication
- Cholesterol Lowering Medication
- Anti-anginal Medication
- Pediatric Medication
- Geriatric Medication
Description
- Combination product containing Amlodipine and Atorvastatin
- Amlodipine Besilate BP equivalent to 5 mg Amlodipine
- Atorvastatin calcium INN equivalent to 10 mg Atorvastatin
- Peripheral arterial vasodilator
- Synthetic lipid-lowering agent
- Inhibitor of 3-hydroxy-3-methyl-glutaryl-coenzyme A
- Usual initial antihypertensive dose is 5 mg once daily
- Recommended starting dose of Atorvastatin is 10 mg daily
Indications
- Hypertension
- Chronic stable angina
- Hypercholesterolemia
- Reduction of risk of nonfatal MI
- Reduction of risk of nonfatal stroke
- Treatment of chronic stable angina
- Treatment of vasospastic angina
Pharmacology
- Reduction in peripheral vascular resistance
- Reduction in blood pressure
- Early and rate limiting step in the synthesis of cholesterol
Dosage & Administration
- Usual initial antihypertensive oral dose is 5 mg
- Maximum dose of 10 mg once daily
- Recommended dose for chronic stable or vasospastic angina is 5-10 mg
- Recommended starting dose of Atorvastatin is 10 mg
Interaction
- Drug interaction with atorvastatin
- Drug interaction with amlodipine
Contraindications
- Known hypersensitivity to Amlodipine
- Hypersensitivity to any component of Atorvastatin
- Active liver disease
Side Effects
- Acute hypotension
- Increased frequency, duration, or severity of angina or acute myocardial infarction on starting calcium channel blocker therapy
- Elevation in serum creatine phosphokinase levels
- Uncomplicated myalgia
Pregnancy & Lactation
- Safety in pregnancy not established
- Not recommended during breastfeeding
Precautions & Warnings
- Increased angina and/or myocardial infarction
- Biochemical abnormalities of liver function
- Potential for acute hypotension
- Use with caution in patients with heart failure
- Rhabdomyolysis with acute renal failure secondary to myoglobinuria
Use in Special Populations
- Safety and efficacy of Atorvastatin not established in children
- Efficacy and safety in older patients using recommended doses similar to general population
Therapeutic Class
- Anti-anginal & lipid lowering drugs
Storage Conditions
- Store in a cool and dry place
- Protect from light and moisture
- Keep out of the reach of children