Leflox TS 1.5% (Ophthalmic Solution)

5 ml drop: ৳ 128.00

Medicine Details

Category Details
Generic Levofloxacin ophthalmic
Company Aci limited
Also available as
Leflox 05 eye drop

Indications

  • Treatment of bacterial conjunctivitis
  • Treatment of bacterial corneal ulcer
  • Treatment of blepharitis
  • Treatment of hordeolum
  • Treatment of perioperative ocular infections
  • Active against Corynebacterium species
  • Active against Staphylococcus aureus
  • Active against Staphylococcus epidermidis
  • Active against Streptococcus pneumoniae
  • Active against Streptococcus (Groups C/F)
  • Active against Streptococcus (Group G)
  • Active against Streptococcus viridans group
  • Active against Acinetobacter lwoffii
  • Active against Haemophilus influenzae
  • Active against Serrotia marcescens

Pharmacology

  • Synthetic broad-spectrum antibiotic
  • Bactericidal
  • Inhibits bacterial topoisomerase IV
  • Inhibits DNA gyrase enzymes
  • Effective against Gram-positive ocular pathogens
  • Effective against Gram-negative ocular pathogens

Dosage & Administration

  • 0.5% eye drop for adults and children 1 year and older
  • 1-2 drops every 2 hours on days 1 and 2
  • 1-2 drops every 4 hours on days 3 through 7
  • 1.5% eye drop for adults and children 6 years and older
  • 1-2 drops every 30 minutes to 2 hours on days 1-3
  • 1-2 drops every 1 to 4 hours from day 4 through treatment completion
  • Safety and effectiveness not established for children under 1 year

Interaction

  • Elevation of plasma concentrations of theophylline
  • Interference with the metabolism of caffeine
  • Enhanced effects of oral anticoagulant warfarin and its derivatives

Contraindications

  • Hypersensitivity to Levofloxacin
  • Hypersensitivity to other quinolones
  • Hypersensitivity to components of the medication

Side Effects

  • Transient blurred vision
  • Fever
  • Foreign body sensation
  • Headache
  • Transient ocular burning
  • Ocular pain or discomfort
  • Pharyngitis
  • Photophobia
  • Allergic reactions
  • Lid edema
  • Ocular dryness
  • Ocular itching

Pregnancy & Lactation

  • Pregnancy Category C
  • Use during pregnancy if potential benefit justifies potential risk to the fetus
  • Caution advised during nursing

Precautions & Warnings

  • Prolonged use may result in overgrowth of non-susceptible organisms
  • Discontinue use if superinfection occurs

Therapeutic Class

  • 4-Quinolone preparations

Storage Conditions

  • Protect from light
  • Store in cool and dry place (15°C-25°C)
  • Keep out of reach of children

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