Defcort 24 mg (Tablet)
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Eskayef pharmaceuticals ltd |
| Also available as |
Title
Defcort
Categories
- Medicine
- Pharmaceuticals
- Glucocorticoids
Description
Defcort is a medication used for indications such as anaphylaxis, asthma, rheumatoid arthritis, systemic lupus erythematosus, ulcerative colitis, nephrotic syndrome, uveitis, and more. It provides anti-inflammatory and immunosuppressive actions through the inhibition of Phospholipase A2 enzyme and modulation of immune system chemicals.
Attributes
- Indications:
- Anaphylaxis
- Asthma
- Rheumatoid arthritis
- Systemic lupus erythematosus
- Ulcerative colitis
- Nephrotic syndrome
- Uveitis
- Pharmacology:
- Inhibition of Phospholipase A2 enzyme
- Immunosuppressive action
- Modulation of immune system chemicals
- Dosage & Administration:
- Adult dosage up to 120 mg/day for acute disorders
- Maintenance doses for most conditions in the range of 3-18 mg/day
- Children's dosage between 0.25-1.5 mg/kg/day
- Gradual withdrawal for patients on high doses for more than 3 weeks
- Interaction:
- Metabolized in the liver
- May require dose adjustment with liver enzyme inducers or inhibitors
- Contraindications:
- Hypersensitivity to Defcort or any of its ingredients
- Patients receiving live virus immunization
- Side Effects:
- GI disturbances
- Musculoskeletal effects
- Endocrine effects
- Neuropsychiatric effects
- Ophthalmic effects
- Fluid and electrolyte disturbances
- Increased susceptibility to infection
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy
- Striae
- Telangiectasia
- Acne
- Cardiovascular effects
- Pregnancy & Lactation:
- Potential risk of intrauterine growth retardation during prolonged or repeated use in pregnancy
- Excretion in breast milk (limited data available)
- Precautions & Warnings:
- Caution in cardiac disease, hypertension, thromboembolic disorders
- Monitoring for salt and water retention, potassium excretion
- Special caution in gastritis, oesophagitis, ulcerative colitis, peptic ulcer
- Monitoring in diabetes mellitus, osteoporosis, myasthenia gravis
- Frequent patient monitoring for several other clinical conditions
- Use in Special Populations:
- Dose adjustment in hepatic impairment
- No special precautions in renally impaired patients and elderly
- Therapeutic Class: Glucocorticoids
- Storage Conditions: Store in a cool and dry place, protected from light and moisture, keep out of the reach of children