Xalcort 30 mg (Tablet)
Unit Price: ৳ 32.00 (1 x 10: ৳ 320.00)
Strip Price: ৳ 320.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Deflazacort |
| Company | Beacon pharmaceuticals plc |
| Also available as |
Indications
- Anaphylaxis
- Asthma
- Severe hypersensitivity reactions
- Rheumatoid arthritis
- Juvenile chronic arthritis
- Polymyalgia rheumatica
- Systemic lupus erythematosus
- Dermatomyositis
- Mixed connective tissue disease
- Polyartritis nodosa
- Sarcoidosis
- Pemphigus
- Bullous pemphigoid
- Pyoderma gangrenosum
- Minimal change nephrotic syndrome
- Acute interstitial nephritis
- Rheumatic carditis
- Ulcerative colitis
- Crohn's disease
- Uveitis
- Optic neuritis
- Autoimmune haemolytic anaemia
- Idiopathic thrombocytopenic purpura
- Acute and lymphatic leukaemia
- Malignant lymphoma
- Multiple myeloma
- Immune suppression in transplantation
Pharmacology
- Anti-inflammatory action
- Inhibition of Phospholipase A2 enzyme
- Prostaglandin synthesis inhibition
- Immunosuppressive action
Dosage & Administration
- Adult dosage up to 120 mg/day
- Maintenance dose in most conditions: 3-18 mg/day
- Children's dosage range: 0.25-1.5 mg/kg/day
- Gradual withdrawal for patients on more than physiological doses
Interaction
Metabolized in the liver. Dose adjustment required with liver enzyme inducers or inhibitors
Contraindications
Hypersensitivity to any ingredients. Patients receiving live virus immunization
Side Effects
- GI disturbances
- Musculoskeletal issues
- Endocrine disturbances
- Neuropsychiatric effects
- Ophthalmic complications
- Fluid and electrolyte disturbances
- Increased susceptibility to infections
- Impaired healing
- Hypersensitivity reactions
- Skin atrophy, striae, and telangiectasia
- Acne
- Myocardial rupture risk
- Thromboembolism
Pregnancy & Lactation
- Risk of intrauterine growth retardation
- Corticosteroids excreted in breast milk
- Possibility of adrenal suppression in infants
Precautions & Warnings
- Cardiac disease or congestive heart failure
- Hypertension
- Thromboembolic disorders
- Gastritis or oesophagitis
- Diverticulitis
- Ulcerative colitis
- Diabetes mellitus
- Osteoporosis
- Myasthenia gravis
- Renal insufficiency
- Emotional instability or psychotic tendency
- Epilepsy
- Liver failure
- Hypothyroidism
- Cirrhosis
- Ocular herpes simplex
Use in Special Populations
- Hepatic Impairment
- Renal Impairment
- Elderly
Therapeutic Class
Glucocorticoids
Storage Conditions
Cool and dry place, protected from light & moisture, keep out of reach of children