Myfocin 500 mg (Tablet)
Medicine Details
| Category | Details |
|---|---|
| Generic | Mefenamic acid |
| Company | Incepta pharmaceuticals ltd |
Indications
- Fever
- Toothache
- Headache
- Migraine
- Primary dysmenorrhoea
- Menorrhagia
- Mild to moderate pain in rheumatoid arthritis and osteoarthritis
- Traumatic pain
- Low-back pain
- Juvenile chronic arthritis in children
Pharmacology
Mefenamic acid contains Mefenamic Acid which is a nonsteroidal agent with demonstrated analgesic, anti-inflammatory and antipyretic activity due to its dual action on prostaglandins. It inhibits the enzymes of prostaglandin synthetase and also antagonizes the actions of prostaglandin at the receptor sites.
Dosage & Administration
- Adult:
- 500 mg dose should be given to adults upto three times (1.5 gm total) per day with meals. The dosage may be reduced to 1 tablet (250 mg) three times daily.
- In case of menorrhagia: 500 mg three times daily with meals and from the onset of menses and continued according to the judgement of the physician.
- Children:
- 6 months to 1 year: 5 ml three times/day.
- 2-4 years: 10 ml three times/day.
- 5-8 years: 10 ml four times /day.
- 9-12 years: 15 ml four times/day.
- Maximum Treatment Duration: 7 days for adults, unless advised by a physician
Interaction
- Aspirin: Concomitant administration of Myfocin and Aspirin is not generally recommended due to potential increased adverse effects.
- Warfarin: Myfocin can inhibit platelet aggregation and may prolong the prothrombin time in patients on warfarin therapy
Contraindications
Known hypersensitivity to Mefenamic Acid, peptic ulcer, inflammatory bowel diseases, hepatic or renal impairment, bronchospasm induced by aspirin and/or other NSAIDs
Side Effects
- Gastrointestinal: abdominal pain, constipation, diarrhoea, dyspepsia, flatulence, nausea, Gl ulcers, vomiting
- Dizziness
- Abnormal renal function
- Pruritus
- Rashes
Pregnancy & Lactation
Use in women of childbearing potential and during pregnancy only when potential benefits outweigh potential risks. Avoid use by nursing mothers due to effects on the infant's cardiovascular system.
Precautions & Warnings
Administer with caution in allergic diseases especially in asthma. Treatment should be withdrawn in case of diarrhoea, rashes, cholestatic jaundice, thrombocytopenia, haemolytic anaemia.
Therapeutic Class
Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Storage Conditions
Keep away from light, store in a cool and dry place. Keep out of reach of children.