Zeroflux (500 mg+267 mg+160 mg)/10 ml (Oral Suspension)

200 ml bottle: ৳ 300.00

Medicine Details

Indications

  • Gastric reflux
  • Heartburn
  • Indigestion
  • Flatulence associated with gastric reflux
  • Heartburn of pregnancy
  • Epigastric distress
  • Retrosternal distress

Pharmacology

  • Combination of Calcium carbonate and Sodium bicarbonate
  • Contains Sodium alginate
  • Neutralizes excess stomach acid
  • Forms protective barrier over stomach contents
  • Does not rely on systemic circulation absorption
  • Forms Alginic Acid gel with near neutral pH
  • Interacts with and caps acid pocket in stomach
  • Reduces esophageal acid exposure
  • Floats on stomach contents to impede gastro-esophageal reflux
  • Protects esophagus from Acid, Pepsin, and Bile
  • Entwines bile and pepsin
  • Fast relief from indigestion and heartburn
  • Increased neutralizing action by Sodium Bicarbonate

Dosage & Administration

  • For oral suspension
  • Adult and children over 12 years: 10-20 mL after meals and at bedtime, up to four times a day
  • Children 6 to 12 years: 5-10 mL after meals and at bedtime, up to four times a day
  • Children under 6 years: Not recommended
  • Elderly: No dose modifications necessary
  • Chewable Tablet for oral route
  • Adults and children 12 years and over: 2-4 tablets after meals and at bedtime, up to four times a day
  • Hepatic Impairment: No dose modification necessary
  • Caution for renal insufficiency with highly restricted salt diet

Interaction

  • Consider time-interval of 2 hours with other medicinal products
  • Especially with Tetracyclines, Digoxine, Fluoroquinolone, Iron salt, Ketoconazole, Neuroleptics, Thyroid Hormones, Penicillamine, beta-blockers, Glucocorticoid, Chloroquine, Biphosphonates and Estramustine

Contraindications

  • Hypersensitivity to active ingredients or excipients

Side Effects

  • Constipation
  • Flatulence
  • Stomach cramp
  • Belching
  • Sensation of swelling with large doses

Pregnancy & Lactation

  • Safe for use during pregnancy if clinically needed
  • No effects shown in breastfed newborns/infants
  • No negative effect on fertility or reproduction

Precautions & Warnings

  • Sodium content of each 20 ml dose: 254.5 mg (11.06 mmol)
  • Calcium content of each 20 ml dose: 260 mg (6.5 mmol)
  • Care needed in hypercalcaemia, nephrocalcinosis, and recurrent calcium containing renal calculi
  • Not generally recommended for children under 12 years without medical advice
  • High in sodium, caution with highly restricted salt diet
  • Contains aspartame, unsuitable for patients with phenylketonuria
  • Consult a physician if symptoms persist or treatment is required for more than 7 days continuously
  • Can mask symptoms of other serious underlying medical conditions
  • Not for use in patients with impaired renal function/insufficiency and hypophosphatemia
  • Potential for allergic reactions

Overdose Effects

  • Symptomatic treatment for abdominal distension

Therapeutic Class

  • Antacids

Storage Conditions

  • Store below 30°C in a cool, dry place away from light
  • Keep out of the reach of children
  • Do not refrigerate or freeze

Common Questions about Zeroflux 500 Suspension

  • Combination of two antacids and an alginate
  • Used to treat Gastric reflux, Heartburn, Indigestion, Flatulence associated with gastric reflux
  • Safe to use during pregnancy and breastfeeding

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