Telmidip 10 mg+40 mg (Tablet)
Unit Price: ৳ 11.00 (3 x 10: ৳ 330.00)
Strip Price: ৳ 110.00
Medicine Details
Category | Details |
---|---|
Generic | Amlodipine besilate telmisartan |
Company | Incepta pharmaceuticals ltd |
Also available as |
Indications
- Treatment of hypertension
- Treatment of hypertension with other antihypertensive agents
- Initial therapy for patients needing multiple drugs to achieve blood pressure goals
Pharmacology
- Fixed dose combination of Telmisartan and Amiodipine
- Telmisartan blocks vasoconstrictor and aldosterone-secreting effects
- Amiodipine inhibits transmembrane influx of calcium ion into vascular smooth muscle and cardiac muscle
Dosage & Administration
- Usual starting dose is 40/5 mg once daily
- Patients requiring larger blood pressure reductions may start with 80/5 mg once daily
- Dosage must be individualized and may be increased after at least 2 weeks
Interactions
- Co-administration of telmisartan did not result in major interaction with various medications
- Amiodipine has been safely administered with several other medications
Contraindications
- Hypersensitivity to the product or its components
- Pregnancy & lactation
- Biliary obstructive disorders, severe hepatic impairment, hypotension, cardiogenic shock, left ventricle outflow tract obstruction
Side Effects
- Dizziness
- Peripheral edema
- Migraine
- Hypotension
- Cough
- Abdominal pain
- Diarrhea
- Nausea
- Pruritus
- Myalgia
- Chest pain
- Fatigue
Pregnancy & Lactation
- Pregnancy Categories C and D
- Potential for adverse effects on nursing infants
Precautions & Warnings
- Avoid fetal or neonatal exposure
- Correct any volume or salt depletion before initiating therapy
- Monitor for worsening heart failure
- Avoid concomitant use of ACE inhibitor and angiotensin receptor blocker
Use in Special Populations
- Safety and effectiveness in pediatric patients not established
- Initial therapy not recommended for patients ≥75 years old or with hepatic impairment
Overdose Effects
- Manifestations of overdose with telmisartan: hypotension, dizziness, tachycardia
- Manifestations of overdose with amiodipine: excessive peripheral vasodilation, marked hypotension
Therapeutic Class
- Combined antihypertensive preparations
Storage Conditions
- Do not store above 30°C
- Protect from light and high humidity
- Keep out of the reach of children