Mobifen 0.1% (Ophthalmic Solution)

Indications

• Pre- and post-operative cover (e.g., for cataract surgery)
• Non-infected chronic conjunctivitis
• Keratoconjunctivitis
• Non-infected post-traumatic conditions of the cornea and conjunctiva

Pharmacology

Blocks the action of cyclo-oxygenase which is involved in the production of prostaglandins causing pain, swelling and inflammation

Dosage & Administration

• Instill 1 drop in the conjunctival sac up to 5 times over the 3 hours preceding surgery
• Instill 1 drop in the conjunctival sac after 15, 30 & 45 minutes following surgery; then 3-5 times daily for as long as required
• Instill 1 drop in the conjunctival sac 4-5 times daily depending on the severity of the diseases

Interaction

No reported drug interactions. At least 5 minutes interval is recommended when another ophthalmic solution (e.g., steroid) is given

Contraindications

Hypersensitivity to any of the components. Contraindicated in patients with history of asthma, urticaria or acute rhinitis following application of acetyl salicylic acid or other cyclo-oxygenase inhibitors

Side Effects

• Mild to moderate burning sensation in 5-15% patients (transient in nature)
• Sensitivity to light
• Bad taste
• Feeling of pressure
• Allergic reactions

Pregnancy & Lactation

Safety not established. Use not recommended unless the potential benefit outweighs the possible risk to the child

Precautions & Warnings

May mask the signs of infection. Physicians should be alert to the development of infections in patients receiving the drug. Periodic eye examinations recommended during prolonged use. Contact lenses should not be worn during treatment

Therapeutic Class

Ophthalmic Non-Steroid drugs

Storage Conditions

Close the bottle immediately after use. Do not use for more than four weeks after opening. Store at room temperature

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