CoxTop 60 mg (Tablet)

Unit Price: ৳ 7.00 (3 x 10: ৳ 210.00)
Strip Price: ৳ 70.00

Medicine Details

Indications

  • Osteoarthritis
  • Rheumatoid arthritis
  • Ankylosing spondylitis
  • Acute gouty arthritis
  • Moderate pain associated with dental surgery

Pharmacology

  • Potent COX-2 specific inhibitor
  • Orally active
  • Inhibition of COX-2 without inhibition of COX-1

Dosage & Administration

  • Recommended doses for different conditions
  • Adjustment of dose based on patient's response
  • Shortest duration and lowest effective daily dose to be used
  • Re-evaluation of patient's need for relief

Interaction

  • Interaction with oral anticoagulants
  • Effect on diuretics and antihypertensive drugs
  • Concomitant use with acetylsalicylic acid
  • Potential increase in nephrotoxic effect of ciclosporin or tacrolimus
  • Impact on lithium levels

Contraindications

  • Hypersensitivity to active substance or excipients
  • Active peptic ulceration or gastrointestinal bleeding
  • Adverse reactions to acetylsalicylic acid or NSAIDs
  • Pregnancy and lactation
  • Severe hepatic dysfunction
  • Estimated renal creatinine clearance
  • Age restriction
  • Inflammatory bowel disease
  • Congestive heart failure
  • Hypertension
  • Ischaemic heart disease and peripheral arterial disease

Side Effects

  • Palpitation
  • Fatigue
  • Influenza-like symptoms
  • Ecchymosis
  • Dry mouth
  • Taste disturbance
  • Mouth ulcer
  • Atrial fibrillation
  • Transient ischaemic attack
  • Chest pain
  • Flushing
  • Cough
  • Dyspnoea
  • Epistaxis
  • Anxiety
  • Impaired mental acuity
  • Paraesthesia
  • Electrolyte disturbance
  • Myalgia and arthralgia
  • Confusion
  • Hallucinations

Pregnancy & Lactation

  • Not recommended in women attempting to conceive
  • Excreted in the milk of lactating rats
  • Advice against breastfeeding while using the medicine

Precautions & Warnings

  • Caution with patients at risk of gastrointestinal complications
  • Consideration for patients with cardiovascular risk factors
  • Potential effect on renal function and blood flow
  • Exercise caution with cardiac failure, left ventricular dysfunction, hypertension, edema, and liver dysfunction
  • Monitoring of liver function
  • Monitoring for hypersensitivity, fever, and signs of inflammation
  • Interaction with warfarin and other oral anticoagulants

Overdose Effects

  • No significant toxicity observed in single or multiple doses up to a certain level
  • Recommendation for supportive measures in case of overdose

Therapeutic Class

  • Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Storage Conditions

  • Temperature requirements
  • Protection from light and moisture
  • Keeping out of reach of children

Chemical Structure

  • Molecular formula
  • Chemical structure image

Common Questions about CoxTop 60 mg Tablet

  • Description of the medicine
  • Duration of effect
  • Onset of action
  • Pregnancy warnings
  • Habit forming tendencies
  • Breastfeeding warnings
  • Safety with alcohol
  • Effect on driving ability
  • Effect on kidney function
  • Effect on liver function
  • Quick tips for patients

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