Ampol Plus 500 mg+65 mg (Tablet)

Unit Price: ৳ 2.50 (20 x 10: ৳ 500.00)
Strip Price: ৳ 25.00

Medicine Details

Category Details
Generic Paracetamol caffeine
Company Al madina pharmaceuticals ltd

Indications

  • Headache
  • Migraine
  • Toothache
  • Neuralgia
  • Feverishness
  • Period pain
  • Sore throat
  • Backache
  • Reduces temperature
  • Aches and pain of colds and flu

Pharmacology

  • Combination of Paracetamol and Caffeine
  • Paracetamol has analgesic and antipyretic properties
  • Caffeine increases solubility and transmembrane permeation of Paracetamol
  • Caffeine increases pain threshold and tolerance of pain
  • Caffeine raises vessel tone in the brain

Dosage & Administration

  • Adult dose: 1-2 tablets every 4-6 hours
  • Maximum adult dose: 8 tablets daily
  • Child dose: Not recommended for children below 12 years

Interactions

  • May reduce serum levels with anticonvulsants
  • May enhance anticoagulant effect of warfarin
  • Accelerated absorption with metoclopramide and domperidone
  • May increase serum levels with probenecid
  • May increase serum levels of chloramphenicol
  • May reduce absorption with colestyramine
  • May cause severe hypothermia with phenothiazine

Contraindications

  • Severe renal function impairment
  • Hepatic disease (Viral Hepatitis)
  • Known hypersensitivity to paracetamol or caffeine

Side Effects

  • Mild side effects for paracetamol
  • Haematological reactions including thrombocytopenia, leukopenia, pancytopenia, neutropenia, and agranulocytosis
  • Pancreatitis
  • Skin rashes
  • Allergic reactions

Pregnancy & Lactation

Consult doctor before taking during pregnancy, can be taken while breastfeeding

Precautions & Warnings

  • Cautious use in hepatic or renal failure
  • Cautious use with other hepatotoxic medication
  • Avoid prolonged use without consulting a physician

Overdose Effects

  • Symptoms in first 24 hours: pallor, nausea, vomiting, anorexia, abdominal pain
  • Liver damage apparent 12 to 40 hours after ingestion
  • Abnormalities of glucose metabolism
  • Metabolic acidosis

Therapeutic Class

Non opioid analgesics

Storage Conditions

Store in a cool and dry place, protect from light and moisture, keep out of reach of children

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