Tufexil 200 mg (Tablet)
Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Tolfenamic acid |
| Company | Al madina pharmaceuticals ltd |
Title
- Tufexil 200 mg Tablet
Categories
- Pain Relief
- Analgesic
- NSAIDs
- Migraine Relief
- Post-operative Pain Relief
- Fever Reducer
Description
- Potent inhibitor of cyclooxygenase enzyme
- Inhibits the synthesis of inflammatory mediators such as thromboxane (TX) B2 and prostaglandin (PG) E2
- Absorbed from GI tract
- Peak plasma concentration: 60-90 min
- Bioavailability: 85%
- Protein-binding: 99%
- Plasma half-life: 2 hours
- Metabolized in the liver
- Excreted in urine (90%) and feces
- Not recommended for use during pregnancy unless considered essential by a doctor
- Not to be given during the third trimester of pregnancy
- Can appear in breast milk in very low concentrations
- Recommended not to be taken while breastfeeding
- Should be taken with food
- Can cause serious complications like stomach bleeding and kidney problems if taken for a long time
- Can raise the risk of blood clots, heart attack, or stroke
- Needs precaution for patients with asthma bronchospasm, bleeding disorders, cardiovascular diseases, peptic ulceration, hypertension, liver infection, cardiac or renal function impairment, and the elderly
- Increase water intake or dose reduction to reduce dysuria
- Store in a cool and dry place, away from light
- Keep out of the reach of children
- Molecular Formula: C14H12ClNO2
- Chemical Structure image available
- Common uses include treatment of acute migraine attacks and mild to moderate pain
- Symptoms of overdose include headache, nausea, vomiting, gastrointestinal bleeding, diarrhea, excitation, coma, drowsiness, dizziness, tinnitus, fainting, and convulsions
- Potential side effects include alveolitis, hepatic damage, pancreatitis, pulmonary eosinophilia, Stevens-Johnson syndrome, angioedema, blood disorder, depression, diarrhea, dizziness, drowsiness, dysuria, euphoria, gastrointestinal bleeding, gastrointestinal discomfort, hallucination, insomnia, malaise, nausea, hearing disturbances, rash, visual disturbances, vertigo, and raised blood pressure
- Therapeutic Class: Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs), Other drugs for migraine
- Interactions with Metoclopramide, Magnesium hydroxide, Aluminium hydroxide, anticoagulants, other NSAIDs, loop diuretics, B-blockers, ACE Inhibitors, Lithium, Methotrexate, cardiac glycosides, ACE inhibitors, Ciclosporin, Tacrolimus, and diuretics
- Contraindications: Active gastrointestinal bleeding, active gastrointestinal ulceration, history of gastrointestinal bleeding related to previous NSAID therapy, history of gastrointestinal hemorrhage, history of gastrointestinal perforation related to previous NSAID therapy, history of recurrent gastrointestinal ulceration, severe heart failure