Algaba 50 mg (Capsule)

Unit Price: ৳ 12.00 (3 x 10: ৳ 360.00)
Strip Price: ৳ 120.00

Medicine Details

Category Details
Generic Pregabalin
Company Al madina pharmaceuticals ltd
Also available as
Algaba 75 mg capsule Algaba 150 mg capsule

Title

  • Algaba 50 mg Capsule

Categories

  • Pain Relief
  • Neurological Medication
  • Anticonvulsant

Description

  • Algaba is indicated for neuropathic pain, postherpetic neuralgia, partial-onset seizures, fibromyalgia, and neuropathic pain associated with spinal cord injury.
  • Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and has high affinity to the alpha2-delta site in the central nervous system.
  • Dosage varies based on indications, patient's age, and creatinine clearance level. Maximum recommended daily doses for different indications are provided. Pregabalin CR capsule dose conversion from pregabalin tablets is also mentioned.
  • Algaba is taken orally and can be taken with or without food. Pregabalin CR tablet should be administered after an evening meal, swallowed whole, and should not be split, crushed, or chewed.
  • Algaba is unlikely to be involved in significant pharmacokinetic drug interactions. There are no significant drug interactions with food or others.
  • Algaba is contraindicated in patients with known hypersensitivity to Pregabalin or any of its components. Not recommended for use during pregnancy and lactation.
  • Precautions and warnings include the possibility of angioedema, increased risk of suicidal thoughts or behavior, potential for respiratory depression, and caution in coadministration with thiazolidinedione antidiabetic agents.
  • Use in special populations is not established for pediatric patients, and it is not recommended during pregnancy and lactation.
  • In case of overdose, reduced consciousness, depression/anxiety, confusional state, agitation, and restlessness can occur. General supportive care and observation of the clinical status of the patient are indicated.
  • Pharmacological class: Adjunct anti-epileptic drugs, Primary anti-epileptic drugs.
  • Storage: Keep in a cool & dry place, protected from light & moisture, and out of the reach of children.

Indications

  • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
  • Postherpetic neuralgia (PHN)
  • Adjunctive therapy for the treatment of partial-onset seizures in patients 1 month of age and older
  • Fibromyalgia
  • Neuropathic pain associated with spinal cord injury

Pharmacology

  • Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • High affinity to the alpha2-delta site in central nervous system tissues

Dosage

  • Neuropathic pain associated with diabetic peripheral neuropathy in adults (DPN): 50-300 mg/day based on efficacy and tolerability
  • Postherpetic neuralgia in adults (PHN): 75-300 mg/day based on efficacy and tolerability
  • Management of fibromyalgia in adults: 300-450 mg/day based on efficacy and tolerability
  • Neuropathic pain associated with spinal cord injury in adults: 150-600 mg/day based on efficacy and tolerability

Administration

  • Route of administration: Oral, with or without food
  • Pregabalin CR tablet administration: After an evening meal, swallow whole, do not split, crush, or chew

Drug interaction

Unlikely to be involved in significant pharmacokinetic drug interactions

Contraindications

Known hypersensitivity to Pregabalin or any of its components

Side effects

  • Dizziness
  • Somnolence
  • Dry mouth
  • Edema
  • Blurred vision
  • Weight gain
  • Difficulty with concentration/attention

Pregnancy lactation

  • Pregnancy: No adequate and well-controlled studies, potential risk to fetus
  • Lactation: Small amounts detected in the milk, not recommended due to potential risk of tumorigenicity

Precautions warnings

  • Angioedema
  • Discontinue immediately in case of hypersensitivity reactions
  • Increased risk of suicidal thoughts or behavior
  • Respiratory depression possible with concomitant CNS depressants or underlying respiratory impairment
  • May cause dizziness and somnolence, caution with driving or operating machinery
  • Withdraw gradually over a minimum of 1 week to avoid increased seizure frequency or adverse reactions
  • May cause peripheral edema, caution with coadministration with thiazolidinedione antidiabetic agents

Use in special populations

  • Use in children and adolescents: Safety and effectiveness not established for specific indications and age groups

Overdose effects

  • Reduced consciousness
  • Depression/anxiety
  • Confusional state
  • Agitation and restlessness
  • Seizures and heart block reported
  • No specific antidote, general supportive care indicated

Storage conditions

Keep in a cool & dry place, protected from light & moisture

Chemical structure

  • Molecular Formula: C8H17NO2
  • Chemical Structure: https://medex.com.bd/storage/res/g-res-919-pregabalin-chemical-structure-dKjKzfuVRrNkwNMBalNK.svg

Common questions and answers

  • What is Algaba 50 mg Capsule?
  • How long do I need to use Algaba 50 mg Capsule before I see improvement in my condition?
  • At what frequency do I need to use Algaba 50 mg Capsule?
  • Should I use Algaba 50 mg Capsule empty stomach, before food or after food?
  • What are the instructions for the storage and disposal of Algaba 50 mg Capsule?
  • Does Algaba 50 mg Capsule work in the same way for each disease?
  • How long do I need to take Algaba 50 mg Capsule?
  • Is it necessary to continue taking Algaba 50 mg Capsule even if I feel fine?
  • Can I take Diazepam and Algaba 50 mg Capsule together?
  • Can the use of Algaba 50 mg Capsule cause weight gain?

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