Atomax 10 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Atorvastatin calcium
Company Al madina pharmaceuticals ltd
Also available as
Atomax 20 mg tablet

Product Title

  • Atomax 10 mg Tablet

Categories

  • Medicine
  • Pharmaceutical

Dosage Form

  • Tablet

Packaging Size

  • 30 tablets
  • 60 tablets
  • 90 tablets

Manufacturer

  • Lorem Ipsum Pharmaceuticals
  • ABC Pharmaceuticals

Chemical Name

  • Atorvastatin Calcium

Therapeutic Class

  • Anti-anginal & Anti-ischaemic drugs
  • Statins

Indications

  • Reduction of total cholesterol and LDL cholesterol in familial hypercholesterolaemia
  • Treatment of mixed dyslipidemia
  • Reduction of serum triglyceride levels in hypertriglyceridaemia
  • Reduction in cardiac ischaemic events in coronary artery disease
  • Reduction of cholesterol concentrations associated with diabetes mellitus or renal transplantation

Pharmacology

  • Selective inhibitor of HMG-CoA reductase
  • Lowers plasma cholesterol and lipoprotein levels
  • Increases hepatic LDL receptors for enhanced uptake and catabolism of LDL

Absorption

  • Rapidly absorbed after oral administration
  • Maximum plasma concentrations occur within 1 to 2 hours
  • Extent of absorption increases with dose

Distribution

  • Mean volume of distribution is approximately 381 liters
  • 98% bound to plasma proteins

Metabolism

  • Extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products
  • Metabolized by cytochrome P450 3A4

Excretion

  • Eliminated primarily in bile
  • Mean plasma elimination half-life is approximately 14 hours

Dosage & Administration

  • Adults: Usually 10 mg once daily; may be increased to max. 80 mg once daily
  • Child (10-18 years): Initially 10 mg once daily, increased if necessary to max. 20 mg once daily

Interaction

  • Increased risk of myopathy with concurrent administration of cyclosporine, fibric acid derivatives, niacin, erythromycin, azole antifungals
  • Plasma concentrations altered when coadministered with antacid, colestipol, digoxin, erythromycin, oral contraceptives, warfarin

Contraindications

  • Hypersensitivity to any component
  • Active liver disease or unexplained elevations of serum transaminases
  • History of serious adverse reaction to prior administration of HMG-CoA reductase inhibitors

Side Effects

  • Constipation
  • Flatulence
  • Dyspepsia
  • Abdominal pain
  • Infection
  • Headache
  • Back pain
  • Rash
  • Asthenia
  • Arthralgia
  • Myalgia

Pregnancy & Lactation

  • Contraindicated during pregnancy
  • Not recommended during breastfeeding

Precautions & Warnings

  • Liver function tests should be performed before initiation of treatment
  • Discontinue therapy if markedly elevated CPK levels occur or myopathy is diagnosed or suspected

Use in Special Populations

  • Geriatric: Higher plasma concentrations in healthy elderly subjects
  • Pediatric: Pharmacokinetic data not available
  • Gender: No clinically significant difference in LDL-C reduction between men and women
  • Renal Insufficiency: No influence on plasma concentrations or LDL-C reduction
  • Hemodialysis: Not expected to significantly enhance clearance
  • Hepatic Insufficiency: Plasma concentrations markedly increased in chronic alcoholic liver disease

Overdose Effects

  • Specific treatment not available
  • Symptomatic treatment and supportive measures instituted
  • Liver function tests and serum CK levels monitored

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Compound Summary

  • Molecular Formula: C33H35FN2O5

Commonly Asked Questions

  • What is Atomax 10 mg Tablet?
  • How should I take Atomax 10 mg Tablet?
  • What are the uses of Atomax 10 mg Tablet?
  • What are the Side Effects of Atomax 10 mg Tablet?
  • What are the instructions for storage and disposal of Atomax 10 mg Tablet?
  • Is Atomax 10 mg Tablet used for lowering cholesterol?
  • Will taking Atomax 10 mg Tablet increase my risk of diabetes?
  • For how long do I need to take Atomax 10 mg Tablet? Is it safe for long-term use?
  • Does Atomax 10 mg Tablet cause weight loss?
  • Can I stop taking Atomax 10 mg Tablet?
  • Does Atomax 10 mg Tablet cause memory loss?
  • Does Atomax 10 mg Tablet make you tired?
  • Can Atomax 10 mg Tablet be prescribed to children?
  • Is Atomax 10 mg Tablet a blood thinner?
  • Quick Tips

Related Brands