BC-Card 5 mg+50 mg (Tablet)
Unit Price: ৳ 6.00 (5 x 10: ৳ 300.00)
Strip Price: ৳ 60.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Amlodipine besilate atenolol |
| Company | Al madina pharmaceuticals ltd |
Title
- Amlodipine and Atenolol Tablet
Categories
- Medicine
- Hypertension
- Angina Pectoris
- Heart Health
Description
- A fixed-dose combination of Amlodipine and Atenolol for essential hypertension and angina pectoris
Dosage
- Recommended dosage of Amlodipine and Atenolol 5/25 mg tablet once daily
- Dosage may be increased to 5/25 mg two tablets daily
Indications
- Indicated for patients with essential hypertension
- Indicated for patients with angina pectoris & hypertension as co-existing diseases
- Indicated for post myocardial infarction patients
- Indicated for patients with refractory angina pectoris where nitrate therapy has failed
Pharmacology
- Amlodipine is a dihydropyridine calcium antagonist that inhibits transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle
- Atenolol is a cardioselective beta-blocker that reduces blood pressure by lowering cardiac output and decreasing sympathetic outflow from CNS
Interaction
- Interaction with Disopyramide leading to additive negative inotropic effects on the heart
- Interaction with Ampicillin at doses of 1 gm and above may reduce Atenolol levels
- Interaction with oral antidiabetics and insulin leading to decreased tissue sensitivity to insulin and inhibited insulin secretion
Contraindications
- Hypersensitivity to either component
- Sinus bradycardia
- Second and higher degrees of heart block
- Cardiogenic shock
- Hypotension
- Congestive heart failure
- Poor left ventricular function
Side effects
- Overall side-effects include fatigue
- Overall side-effects include headache
- Overall side-effects include edema
- Overall side-effects include nausea
- Overall side-effects include drowsiness
- Overall side-effects include anxiety
- Overall side-effects include depression
Pregnancy lactation
- Use during pregnancy if expected benefit outweighs potential fetal risk
- Not recommended for nursing mothers
Precautions warnings
- Use with caution in patients with airway obstruction
- Can be used in patients with renal impairment, caution if creatinine clearance is less than 30 ml/min
- Caution in use for patients with severe liver damage due to prolongation of the elimination half-life of Amlodipine
- Patients should be warned against stopping the drug suddenly, any discontinuation should be gradual and under observation
Overdose effects
- Hypotension and less frequently congestive cardiac failure may occur in cases of overdosage
- Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal
- Symptomatic treatment is suggested
Therapeutic class
- Combined antihypertensive preparations
Storage conditions
- Keep below 30°C temperature
- Store away from light & moisture
- Keep out of the reach of children