Terbiheal 250 mg (Tablet)

Unit Price: ৳ 50.00 (1 x 10: ৳ 500.00)
Strip Price: ৳ 500.00

Medicine Details

Title

  • Terbiheal Tablet
  • Terbiheal Granules
  • Terbiheal Cream
  • Terbiheal 1% Spray

Basic Information

  • Antifungal Medication
  • Allylamine Antifungal

Indications

  • Treatment of onychomycosis of toenail
  • Treatment of onychomycosis of fingernail
  • Treatment of Tinea Capitis
  • Treatment of fungal infections of the skin
  • Treatment of yeast infections of the skin
  • Treatment of pityriasis versicolor

Pharmacology

  • Inhibition of Ergosterol biosynthesis
  • Inhibition of Squalene Epoxidase enzyme
  • Fungicidal against specific microorganisms

Dosage & Administration

  • 250 mg tablet daily for 6 weeks for fingernail onychomycosis
  • 250 mg tablet daily for 12 weeks for toenail onychomycosis
  • Different dosages based on body weight for granules
  • Once or twice daily application for cream
  • Once or twice daily application for 1% spray

Interaction

  • Inhibition of CYP450 2D6 isozyme
  • Careful co-administration with specific drug classes

Contraindications

  • Hypersensitivity to terbinafine

Side Effects

  • Gastrointestinal symptoms
  • Liver test abnormalities
  • Rashes
  • Urticaria
  • Pruritus
  • Taste disturbances
  • Idiosyncratic and symptomatic hepatic injury
  • Serious skin reactions
  • Severe neutropenia
  • Thrombocytopenia
  • Angioedema
  • Allergic reactions
  • Malaise
  • Fatigue
  • Vomiting
  • Arthralgia
  • Myalgia
  • Hair loss

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Terbinafine present in breast milk
  • Excreted in breast milk

Precautions & Warnings

  • Rare cases of liver failure
  • Discontinue if evidence of liver injury
  • Discontinue in case of progressive skin rash
  • External use only for cream
  • Avoid contact with eyes for cream
  • Not recommended for patients with chronic or active liver disease
  • Assessment of pre-existing liver disease before prescribing
  • Pretreatment serum transaminase test for all patients before taking terbinafine tablets

Use in Special Populations

  • Safety and efficacy not established in pediatric patients
  • No evidence of different dosages or side-effects in elderly patients

Overdose Effects

  • Limited clinical experience
  • Doses up to 5 gm taken without serious adverse reactions

Therapeutic Class

  • Antifungal Preparations

Storage Conditions

  • Store below 30°C
  • Protect from light

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