Twindopa 100 mg+10 mg (Tablet)
Unit Price: ৳ 7.02 (3 x 10: ৳ 210.60)
Strip Price: ৳ 70.20
Medicine Details
| Category | Details |
|---|---|
| Generic | Levodopa carbidopa fc tablet |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Parkinson's disease treatment
- Relieves rigidity and bradykinesia
- Manage tremor and dysphagia
- Post-stroke motor recovery aid
- Sialorrhea management
Description
- Levodopa metabolic precursor of dopamine
- Carbidopa reduces peripheral metabolism of Levodopa
Dosage & Administration
- Initiation with 100/10 mg tablet
- Titration for optimum carbidopa dosage
- Starting dosage for 250/25 mg tablet
- Maintenance dose individualization
Interaction
- Symptomatic postural hypotension risk
- Dosage adjustment with antihypertensive meds
- Bioavailability reduction with ferrous sulphate
- Decreased therapeutic effects with dopamine-2 receptor antagonists
Contraindications
- Hypersensitivity to Carbidopa or Levodopa
- Narrow-angle glaucoma
- Suspected melanoma or history of melanoma
Side Effects
- Dyskinesias including choreiform movements
- Central neuropharmacologic adverse effects
- Cardiovascular and gastrointestinal adverse effects
- Nervous system-related adverse effects
Pregnancy & Lactation
- Unknown effects on human pregnancy
- Visceral and skeletal malformations in animal studies
Precautions & Warnings
- Not recommended for extrapyramidal reactions
- Observation for depression and suicidal tendencies
- Cautious administration in patients with cardiovascular or pulmonary disease
Use in Special Populations
- Not recommended for patients below 18 years
Therapeutic Class
- Antiparkinson drugs
Storage Conditions
- Store in a cool and dry place, protected from light