Twindopa 100 mg+25 mg (Tablet)
Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levodopa carbidopa fc tablet |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Treatment of Parkinson's disease and syndrome
- Relief from rigidity and bradykinesia
- Management of tremor, dysphagia, sialorrhea
- Useful in postural instability
- Motor recovery after stroke
Description
- Levodopa precursor crosses blood-brain barrier
- Carbidopa inhibits peripheral metabolism of Levodopa
Dosage & Administration
- Initiate dosage with one tablet three or four times a day
- Titration upward may be required in some patients
- Individualized therapy for maintenance dose
Interaction
- Potential interactions with antihypertensive medicines
- Possible impact of tricyclic antidepressants on efficacy
- Bioavailability decrease with ingestion of iron supplements
- Reduced therapeutic effects with dopamine-2 receptor antagonists
- Careful observation for loss of therapeutic response with specific medicines
Contraindications
- Hypersensitivity to Carbidopa and Levodopa
- Narrow-angle glaucoma
- Suspicious undiagnosed skin lesions or history of melanoma
Side Effects
- Central neuropharmacologic activity of dopamine
- Common adverse effects: dyskinesias, nausea
- Adverse effects in various body systems
Pregnancy & Lactation
- Unknown effects on human pregnancy
- Potential hazards in women of childbearing potential
- Decision-making for nursing mothers
Precautions & Warnings
- Not recommended for medicine-induced extrapyramidal reactions
- Observation for depression with suicidal tendencies
- Cautious administration in patients with various diseases
- Monitoring cardiac function in patients with history of myocardial infarction
- Careful treatment of patients with chronic wide-angle glaucoma
Use in Special Populations
- Safety and effectiveness not established in infants and children
Therapeutic Class
- Antiparkinson drugs
Storage Conditions
- Cool and dry place, protected from light