Neurocet XR 500 mg (Tablet (Extended Release))
Unit Price: ৳ 30.00 (2 x 10: ৳ 600.00)
Strip Price: ৳ 300.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levetiracetam |
| Company | Incepta pharmaceuticals ltd |
| Also available as |
Indications
- Monotherapy in the treatment of partial-onset seizures
- Adjunctive therapy for partial-onset seizures in all age groups
- Treatment of myoclonic seizures in Juvenile Myoclonic Epilepsy
- Treatment of primary generalized tonic-clonic seizures in Idiopathic Generalised Epilepsy
Description
- Precise mechanism(s) unknown for antiepileptic effect
- Minimal activity in submaximal stimulation
- Protection against secondarily generalized activity
- Inhibits burst firing without affecting normal neuronal excitability
Dosage
- Recommended starting dose of 250 mg twice daily
- Maximum dose of 1500 mg twice daily for adults
- Different dosing regimen for pediatric population
- Dose adjustments based on clinical response and tolerability
Administration
- Oral administration with liquid
- Dosage divided into two equal parts daily
Interactions
- No influence on serum concentrations of existing antiepileptic drugs
- Inhibitory effect with probenecid on metabolite clearance
- Monitor methotrexate levels when co-administered
- Avoid concurrent use with osmotic laxatives like macrogol
Contraindications
- Hypersensitivity to active substance or excipients
Side Effects
- Common adverse reactions include somnolence and asthenia in adults
- Pediatric patients may experience fatigue and decreased appetite
Pregnancy & Lactation
- Not recommended during pregnancy or breastfeeding
- Excreted in human breast milk
- Impact on fertility unknown in humans
Precautions & Warnings
- Dose adjustment for renal impairment
- Rare cases of decreased blood cell counts reported
- Risk of suicidal thoughts and behavior in patients
- Monitor patients for signs of depression and suicidal ideation
Use in Special Populations
- Dose adjustment recommended for elderly and renal impairment
- No dose adjustment needed for mild to moderate hepatic impairment
Overdose Effects
- Symptoms include somnolence and respiratory depression
- No specific antidote available
- Treatment is symptomatic and may include haemodialysis
Therapeutic Class
- Belongs to adjunct anti-epileptic drugs
Storage Conditions
- Store at temperature not exceeding 25°C
- Keep in a dry place and protect from light