Oxyfer 1 gm/20 ml (IV Injection or Infusion)

20 ml vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Ferric carboxymaltose
Company Ibn sina pharmaceuticals ltd
Also available as
Oxyfer 500 mg injection Oxyfer 750 mg injection

Indications

  • Treatment of iron deficiency anaemia in adults
  • Intolerance to oral iron
  • Non-dialysis dependent chronic kidney disease

Description

  • Colloidal iron (III) hydroxide in complex with Carboxymaltose
  • Carbohydrate polymer that releases iron

Dosage & Administration

  • Stepwise approach to posology
  • Determination of individual iron need based on body weight and haemoglobin level
  • Calculation and administration of iron dose(s)
  • Post-iron repletion assessments
  • Administering Ferric Carboxymaltose based on individual need
  • Maximum recommended cumulative dose of Ferric Carboxymaltose per week

Interaction

  • Formal drug interaction studies not performed

Contraindications

  • Hypersensitivity to the active substance or any excipients
  • Serious hypersensitivity to other parenteral iron products
  • Anaemia not attributed to iron deficiency
  • Evidence of iron overload or disturbances in iron utilization

Side Effects

  • Infrequent and mild side effects
  • Nausea, headache, dizziness, hypertension, injection site reactions
  • Laboratory test alterations
  • Various uncommon and rare side effects

Pregnancy & Lactation

  • No adequate and well-controlled trials in pregnant women
  • Animal data suggesting potential influence on fetal skeletal development
  • Limited data on breastfeeding women

Precautions & Warnings

  • Serious hypersensitivity reactions reported
  • Monitoring for signs and symptoms of hypersensitivity
  • Transient elevations in systolic blood pressure
  • Laboratory assay alterations in the 24 hours following administration

Use in Special Populations

  • Special considerations for patients with haemodialysis-dependent chronic kidney disease
  • Not recommended for children under 14 years

Overdose Effects

  • Potential accumulation of iron in storage sites
  • Monitoring of iron parameters
  • Consideration of iron chelator use

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Store below 30°C in a cool and dry place
  • Away from light
  • Do not freeze
  • Keep out of the reach of children

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