Injefer 1 gm/20 ml (IV Injection or Infusion)

20 ml vial: ৳ 1,300.00

Medicine Details

Category Details
Generic Ferric carboxymaltose
Company Opsonin pharma ltd
Also available as
Injefer 100 mg injection Injefer 500 mg injection

Indications

  • Treatment of iron deficiency anaemia in adult patients who have intolerance to oral iron
  • Treatment of iron deficiency anaemia in adult patients with non-dialysis dependent chronic kidney disease

Description

  • Colloidal iron (III) hydroxide in complex with Carboxymaltose
  • Carbohydrate polymer that releases iron

Dosage & Administration

  • Stepwise approach for posology of Ferric Carboxymaltose
  • Determination of individual iron need based on body weight and haemoglobin level
  • Calculation and administration of iron dose(s) based on individual iron need
  • Post-iron repletion assessments by the clinician

Interaction

  • Formal drug interaction studies have not been performed

Contraindications

  • Hypersensitivity to the active substance, Ferric Carboxymaltose, or any of its excipients
  • Serious hypersensitivity to other parenteral iron products
  • Anaemia not attributed to iron deficiency
  • Evidence of iron overload or disturbances in iron utilization

Side Effects

  • Infrequent and mild side effects
  • Common side effects: nausea, headache, dizziness, hypertension, injection site reactions
  • Uncommon side effects: dysgeusia, tachycardia, hypotension, diarrhea, myalgia
  • Rare side effects: anaphylactoid reactions, loss of consciousness, bronchospasm

Pregnancy & Lactation

  • No adequate and well-controlled trials in pregnant women
  • Careful benefit/risk evaluation required for use during pregnancy
  • Unlikely risk to breastfed child based on limited data

Precautions & Warnings

  • Serious hypersensitivity reactions reported
  • Monitor patients for signs and symptoms of hypersensitivity
  • Transient elevations in systolic blood pressure may occur
  • Laboratory test alterations in the 24 hours following administration

Use in Special Populations

  • Maximum daily injection dose in haemodialysis-dependent chronic kidney disease patients
  • Not recommended in children under 14 years

Overdose Effects

  • Excessive dosages may lead to accumulation of iron in storage sites
  • Monitoring of iron parameters such as serum ferritin and transferrin saturation may help in recognizing iron accumulation

Therapeutic Class

  • Parenteral Iron Preparations

Storage Conditions

  • Store in a cool and dry place below 30°C
  • Keep away from light and do not freeze
  • Keep out of the reach of children

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