Injefer 500 mg/10 ml (IV Injection or Infusion)

10 ml vial: ৳ 700.00

Medicine Details

Category Details
Generic Ferric carboxymaltose
Company Opsonin pharma ltd
Also available as
Injefer 1 gm injection Injefer 100 mg injection

Therapeutic Class

  • Parenteral Iron Preparations

Indications

  • Treatment of iron deficiency anaemia in adult patients
  • Intolerance to oral iron
  • Non-dialysis dependent chronic kidney disease

Description

  • Colloidal iron (III) hydroxide in complex with Carboxymaltose

Dosage & Administration

  • Stepwise approach for determination, calculation, and administration of iron dose
  • Posology based on individual iron need, body weight, and haemoglobin level
  • Maximum individual iron dose not to exceed 15 mg iron/kg body weight

Interaction

  • No formal drug interaction studies performed

Contraindications

  • Hypersensitivity to active substance or any excipients
  • Serious hypersensitivity to other parenteral iron products
  • Anaemia not attributed to iron deficiency
  • Evidence of iron overload or disturbances in iron utilisation

Side Effects

  • Infrequent and mild side effects
  • Common: nausea, headache, dizziness, hypertension, injection site reactions
  • Uncommon: hypersensitivity, tachycardia, flushing, abdominal pain, diarrhea
  • Rare: anaphylactoid reactions, loss of consciousness, bronchospasm, malaise

Pregnancy & Lactation

  • No adequate and well-controlled trials in pregnant women
  • Use during pregnancy requires careful benefit/risk evaluation
  • Unlikely risk to breast-fed child based on limited data

Precautions & Warnings

  • Monitor for signs of hypersensitivity during and after administration
  • Immediate availability of personnel and therapies for serious reactions
  • Monitor for hypertension following administration
  • 24-hour post-administration may overestimate serum iron in lab tests

Use in Special Populations

  • Single maximum daily injection dose of 200 mg iron in haemodialysis-dependent chronic kidney disease patients
  • Not recommended in children under 14 years

Overdose Effects

  • Excessive dosages may lead to iron accumulation in storage sites
  • Monitor iron parameters for recognition of accumulation
  • Consider use of iron chelator if iron accumulation has occurred

Storage Conditions

  • Store in cool (below 30°C) and dry place
  • Keep away from light and do not freeze
  • Keep out of the reach of children

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