Cilnior 10 mg (Tablet)
Unit Price: ৳ 9.00 (3 x 10: ৳ 270.00)
Strip Price: ৳ 90.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cilnidipine |
| Company | Orion pharma ltd |
| Also available as |
Title
- Cilnior
Categories
- Medicine
- Pharmaceutical
Description
- Cilnior is indicated for the management of hypertension for end-organ protection. It is reported to be useful in elderly patients and in those with diabetes and albuminuria. Cilnior has been increasingly used in patients with chronic kidney disease. Cilnidipine is a dihydropyridine calcium-channel blocker. Cilnidipine binds to the dihydropy-ridine binding sites of the L-type voltage dependent calcium channel and inhibits Ca²⁵ influx across the cell membranes of vascular smooth muscle cells via this channel, consequently vascular smooth muscle is relaxed, causing vasodilation.
Dimensions
- Standard pharmaceutical packaging size
Color Options
- Not applicable
Functions
- Manages hypertension for end-organ protection
- Causes vasodilation
- Inhibits Ca²⁵ influx across the cell membranes of vascular smooth muscle cells
Materials
- Active ingredient: Cilnidipine
Technical Specifications
- Dihydropyridine calcium-channel blocker
Design Elements
- Standard pharmaceutical design
Usability Features
- Once daily dosage after breakfast for adults: 5-10 mg
- Maximum dose: 20 mg once daily
Dosage
- Adults: 5-10 mg once daily after breakfast
- Maximum dose: 20 mg once daily
- Pediatric use: The safety of Cilnidipine in pediatric patients has not been established
- Elderly use: Initiated with the lowest possible dose (5 mg)
Interactions
- Other anti-hypertensive medications
- Antipsychotics causing hypotension
- Quinidine
- Carbamazepine
- Phenytoin
- Rifampicin
- Cimetidine
- Erythromycin
Contraindications
- Known sensitivity to Cilnidipine or any excipients
- Cardiogenic shock
- Recent MI or acute unstable angina
- Severe aortic stenosis
Side Effects
- Dizziness
- Flushing
- Headache
- Hypotension
- Peripheral edema
- Palpitations
- GI disturbances
- Increased micturition frequency
- Lethargy
- Eye pain
- Depression
Pregnancy & Lactation
- Not to be administered in pregnant or potentially pregnant women
- Avoid administration to nursing mothers
- Discontinue lactation if administration is indispensable
Precautions & Warnings
- Administration with care in patients with serious hepatic dysfunction
- Patients with a history of serious adverse reactions to calcium antagonists
- Dosage should be gradually decreased during discontinuation under close observation
Therapeutic Class
- Calcium-channel blockers
Storage Conditions
- Store below 30°C
- Protected from light and moisture
- Keep away from reach of children