Nervalin 100 mg/5 ml (Oral Solution)

100 ml bottle: ৳ 220.00

Medicine Details

Category Details
Generic Pregabalin
Company Beximco pharmaceuticals ltd
Also available as
Nervalin 50 mg capsule Nervalin 75 mg capsule Nervalin 25 mg capsule Nervalin cr 330 mg tablet Nervalin cr 825 mg tablet Nervalin cr 165 mg tablet

Title

Nervalin 100 mg/5 ml Oral Solution

Categories

  • Pain Relief
  • Neuropathy Treatment
  • Anticonvulsant
  • Fibromyalgia Management

Description

Nervalin is a medication used for neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, spinal cord injury, and as adjunctive therapy for partial-onset seizures. It has a pharmacological action related to the binding of the alpha2-delta subunit, and its dosage varies for different indications. It is administered orally, and precautions need to be taken for specific populations and situations such as pregnancy, lactation, and overdose. The medication has contraindications, potential drug interactions, side effects, and storage requirements.

Attributes

  • Indications:
    • Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
    • Postherpetic neuralgia (PHN)
    • Adjunctive therapy for the treatment of partial-onset seizures
    • Fibromyalgia
    • Neuropathic pain associated with spinal cord injury
  • Maximum Recommended Dose: 100 mg three times a day for DPN, 75 to 150 mg two times a day or 50 to 100 mg three times a day for PHN, 300 to 450 mg/day for fibromyalgia, 150 to 600 mg/day for spinal cord injury
  • Route of Administration: Oral
  • Dosage Form: Oral Solution
  • Dosage Range: 50 mg to 600 mg/day
  • Recommended Starting Dose: 50 mg three times a day for DPN, 75 mg two times a day or 50 mg three times a day for PHN, 75 mg two times a day for fibromyalgia, 75 mg two times a day for spinal cord injury
  • Administration Instructions: Swallow whole, do not split, crush or chew, administer after an evening meal
  • Missed Dose Instructions:
    • Take missed dose after an evening meal, followed by the usual dose prior to bedtime after a snack
    • If dose is missed prior to bedtime, take it following a morning meal
    • If dose is missed following the morning meal, take it at the usual time that evening after an evening meal
  • Discontinuation Instructions: Gradually taper over a minimum of 1 week
  • Potential Drug Interactions: Unlikely to be involved in significant pharmacokinetic drug interactions
  • Common Side Effects in Adults:
    • Dizziness
    • Somnolence
    • Dry Mouth
    • Edema
    • Blurred Vision
    • Weight Gain
    • Thinking Abnormal
  • Side Effects in Pediatric Patients:
    • Increased Weight
    • Increased Appetite
  • Pregnancy & Lactation:
    • Category: Not recommended during pregnancy
    • Lactation: Not recommended due to potential risk of tumorigenicity
  • Warnings:
    • Angioedema: Discontinue immediately if occurring
    • Hypersensitivity Reactions: Discontinue immediately if occurring
    • Suicidal Thoughts: Increased risk with Nervalin
    • Respiratory Depression: May occur with concomitant CNS depressants or respiratory impairment
    • Drowsiness: May impair ability to drive or operate machinery
    • Seizure Frequency: May increase if Nervalin is rapidly discontinued
    • Peripheral Edema: May cause, exercise caution when coadministering with thiazolidinedione antidiabetic agents
  • Use in Children and Adolescents:
    • Safety and Effectiveness: Not established for several indications
  • Overdose Effects:
    • Reduced Consciousness
    • Depression/Anxiety
    • Confusional State
    • Agitation
    • Restlessness
    • Seizures
    • Heart Block
  • Therapeutic Class:
    • Adjunct Anti-epileptic Drugs
    • Primary Anti-epileptic Drugs
  • Storage Conditions: Keep in a cool & dry place (below 30°C), protected from light & moisture, keep out of the reach of children

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