Emlino 25 mg+5 mg (Tablet)

Unit Price: ৳ 40.00 (2 x 10: ৳ 800.00)
Strip Price: ৳ 400.00

Medicine Details

Category Details
Generic Empagliflozin linagliptin
Company Acme laboratories ltd
Also available as
Emlino 10 mg tablet

Indications

  • Adjunct to diet and exercise
  • Improves glycemic control
  • For adults with type 2 diabetes mellitus

Pharmacology

  • Inhibits DPP-4 enzyme
  • Increases active incretin hormones
  • Stimulates insulin release
  • Decreases glucagon levels
  • Inhibitor of Sodium-glucose co-transporter 2
  • Reduces renal reabsorption of glucose

Dosage & Administration

  • Recommended dose: 10 mg Empagliflozin + 5 mg Linagliptin once daily
  • Increased dose: 25 mg Empagliflozin + 5 mg Linagliptin once daily
  • Renal impaired patients assessment required

Interaction

  • Coadministration with diuretics increases urine volume
  • Coadministration with Insulin or Insulin secretagogues increases hypoglycemia risk
  • Rifampin decreases Linagliptin exposure
  • Increases urinary glucose excretion
  • Interferes with 1,5-anhydroglucitol (1,5-AG) Assay

Contraindications

  • Severe renal impairment, end-stage renal disease, or dialysis
  • History of hypersensitivity reaction to Linagliptin or Empagliflozin

Side Effects

  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia with Insulin and Insulin Secretagogues
  • Necrotizing Fasciitis of the Perineum (Fournier's Gangrene)
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Severe and Disabling Arthralgia
  • Bullous Pemphigoid
  • Heart Failure

Pregnancy & Lactation

  • Not recommended during second and third trimesters
  • Limited available data in pregnant women
  • Risks associated with poorly controlled diabetes in pregnancy

Precautions & Warnings

  • Hypotension
  • Acute kidney injury
  • Genital Mycotic Infections
  • Heart Failure
  • Pancreatitis
  • Ketoacidosis
  • Volume Depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia

Overdose Effects

  • Contact Poison Control Center in case of overdose
  • Employ usual supportive measures
  • Hemodialysis not studied for removal of Empagliflozin
  • Removal of Linagliptin by hemodialysis or peritoneal dialysis is unlikely

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Store below 30°C
  • Keep away from light and wet place
  • Keep out of reach of children

Related Brands