Levefix 500 mg/5 ml (Oral Solution)
50 ml bottle: ৳ 200.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Levetiracetam |
| Company | Opsonin pharma ltd |
| Also available as |
Indications
- Monotherapy for partial-onset seizures in adults and adolescents
- Adjunctive therapy for partial-onset seizures in adults, adolescents, children, and infants
- Treatment of myoclonic seizures in adults and adolescents
- Treatment of primary generalized tonic-clonic seizures in adults and adolescents
Description
- Precise mechanism of action is unknown
- Minimal activity in submaximal stimulation and threshold tests
- Inhibition of burst firing without affecting normal neuronal excitability
Dosage
- Initial starting dose of 250 mg twice daily for adults and adolescents
- Maximum dose of 1500 mg twice daily
- Different dosage recommendations for pediatric population
- Tablet formulation not suitable for infants and young children
Administration
- Oral administration with sufficient quantity of liquid
- Administered in two equally divided doses
- Can be taken with or without food
Interaction
- No influence on serum concentrations of existing antiepileptic medicinal products
- Interaction with probenecid, methotrexate, and laxatives reported
- Effect of food and alcohol on absorption
Contraindications
- Hypersensitivity to the active substance or other pyrrolidone derivatives
Side Effects
- Common adverse reactions in adult and pediatric patients
Pregnancy & Lactation
- Not recommended during pregnancy and breastfeeding
- Excretion in human breast milk
Precautions & Warnings
- Dose adjustment required for renal impairment
- Rare cases of decreased blood cell counts reported
- Association with acute kidney injury
- Monitoring for signs of depression and suicidal ideation
- Use in elderly, renal impairment, and hepatic impairment
Use in Special Populations
- Dose adjustment in elderly and patients with compromised renal function
- Individualized dose according to renal function
Overdose Effects
- Observation of somnolence, agitation, depression, respiratory depression, and coma
- No specific antidote available
- Symptomatic treatment may include haemodialysis
Therapeutic Class
- Adjunct anti-epileptic drugs
Storage Conditions
- Store at a cool temperature not exceeding 25°C
- Keep in a dry place protected from light