Levefix 500 mg (Tablet)

Unit Price: ৳ 30.00 (1 x 10: ৳ 300.00)
Strip Price: ৳ 300.00

Medicine Details

Indications

  • Monotherapy in the treatment of partial-onset seizures
  • Adjunctive therapy for partial-onset seizures
  • Treatment of myoclonic seizures
  • Treatment of primary generalized tonic-clonic seizures

Description

  • Precise mechanism of action unknown
  • Minimal activity in submaximal stimulation
  • Protection against secondarily generalized activity from focal seizures induced by chemo-convulsants

Dosage

  • Recommended starting dose for adults and adolescents
  • Initial therapeutic dose for adults and adolescents
  • Maximum dose for adults and adolescents
  • Dosing information for pediatric population

Administration

  • Oral administration
  • Swallowed with sufficient liquid
  • Taken with or without food
  • Administered in two equally divided doses

Interaction

  • Interaction with antiepileptic medicinal products
  • Interaction with probenecid
  • Interaction with methotrexate
  • Interaction with laxatives
  • Effect of food and alcohol on absorption

Contraindications

  • Hypersensitivity to the active substance or other pyrrolidone derivatives or excipients

Side Effects

  • Common adverse reactions in adult patients
  • Common adverse reactions in pediatric patients

Pregnancy & Lactation

  • Not recommended during pregnancy
  • Not recommended during breastfeeding
  • Impact on fertility not detected in animal studies

Precautions & Warnings

  • Dose adjustment for patients with renal impairment
  • Potential association with acute kidney injury
  • Rare cases of decreased blood cell counts
  • Risk of suicidal thoughts and behavior
  • Impact on growth, puberty, and childbearing potential in children unknown

Use in Special Populations

  • Adjustment of dose in elderly patients with compromised renal function
  • Dose individualization according to renal function in renal impairment
  • Dose adjustment in severe hepatic impairment

Overdose Effects

  • Observations with Levefix overdoses
  • Symptomatic treatment
  • No specific antidote
  • Possible haemodialysis

Therapeutic Class

  • Adjunct anti-epileptic drugs

Storage Conditions

  • Storage at cool temperature (not exceeding 25°C)
  • Dry place
  • Protected from light

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