Cafecool Plus 500 mg+65 mg (Tablet)

Unit Price: ৳ 2.50 (10 x 10: ৳ 250.00)
Strip Price: ৳ 25.00

Medicine Details

Indications

  • Headache
  • Migraine
  • Toothache
  • Neuralgia
  • Feverishness
  • Period pain
  • Sore throat
  • Backache
  • Help to reduce the temperature
  • Aches and pain of colds and flu

Pharmacology

  • Combination of Paracetamol and Caffeine
  • Analgesic and antipyretic properties with weak anti-inflammatory activity
  • Theophylline-like xanthine derivative
  • Increases solubility and transmembrane permeation of Paracetamol
  • Increases pain threshold and tolerance of pain
  • Raises vessel tone in the brain

Dosage & Administration

  • Adult dose: 1-2 tablets every 4-6 hours
  • Maximum dose: 8 tablets daily
  • Not recommended for children below 12 years

Interaction

  • May reduce serum levels with anticonvulsants
  • May enhance the anticoagulant effect of warfarin and other coumarins with prolonged use
  • Accelerated absorption with metoclopramide and domperidone
  • May increase serum levels with probenecid
  • May increase serum levels of chloramphenicol
  • May reduce absorption with colestyramine within 1 hr of admin
  • May cause severe hypothermia with phenothiazine

Contraindications

  • Severe renal function impairment
  • Hepatic disease (Viral Hepatitis)
  • Known hypersensitivity to paracetamol or caffeine

Side Effects

  • Mild side effects
  • Haematological reactions
  • Thrombocytopenia
  • Leukopenia
  • Pancytopenia
  • Neutropenia
  • Agranulocytosis
  • Pancreatitis
  • Skin rashes
  • Allergic reactions

Pregnancy & Lactation

  • Consultation required during pregnancy
  • Safe for breastfeeding mothers

Precautions & Warnings

  • Cautious use in hepatic or renal failure
  • In patients taking other hepatotoxic medication
  • Prolonged use without consulting a physician

Overdose Effects

  • Symptoms of Paracetamol overdose
  • Liver damage
  • Abnormalities of glucose metabolism
  • Metabolic acidosis

Therapeutic Class

  • Non opioid analgesics

Storage Conditions

  • Cool and dry place
  • Protection from light and moisture
  • Keep out of the reach of children

Related Brands