Mebel DS 400 mg (Chewable Tablet)
Unit Price: ৳ 5.00 (25 x 2: ৳ 250.00)
Strip Price: ৳ 10.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Albendazole |
| Company | Medicon pharmaceuticals ltd |
| Also available as |
Indications
- Hookworm infestation
- Roundworm infestation
- Threadworm infestation
- Whipworm infestation
- Strongyloides infestation
- Tapeworm infestation
- Opisthorchi infestation
- Hydatid disease treatment
Description
- Benzimidazole anthelmintic
- Active against nematodes and some cestodes
- Vermicidal, ovicidal, and larvicidal activity
- Inhibitory effect on tubulin polymerization
Pharmacology
- Broad spectrum anthelmintic
- Blocks glucose uptake in helminths
- Exerts anthelmintic effect by immobilizing the parasite
- Extensively metabolized, probably in the liver
- Poorly absorbed from the gastrointestinal tract
- Binds to human tubulin
Dosage & Administration
- Recommended dosage for adults and children over 2 years
- Recommended dosage for children of 1-2 years
- Not recommended for children under 1 year
- Specific dosage for hydatid disease (Echinococcosis)
- Dosage for giardiasis
Interaction
- No reported pharmacodynamic interactions
- No reported pharmacokinetic interactions
Contraindications
- Not normally used in neonates
- Consider reduction of the dose in children weighing less than 10 kg
- Not recommended during pregnancy or in women thought to be pregnant
- No evidence to suggest dose alteration in renal, hepatic, or cardiac failure
Side Effects
- Gastrointestinal disturbances
- Headache
- Dizziness
- Changes in liver enzymes
- Rarely reversible alopecia
- Rash
- Fever
- Blood disorders including leucopenia and pancytopenia
- Allergic shock if cyst leakage
- Convulsions and meningism in cerebral disease
Pregnancy & Lactation
- US FDA Pregnancy category - C
- Avoid in pregnancy and lactation
- Assess potential benefits against possible risks to the fetus
Precautions & Warnings
- Blood counts and liver function tests before treatment and during each cycle
- Caution if breastfeeding
- Pregnancy exclusion before starting treatment
- Constant medical supervision in the treatment of Echinococcosis
Therapeutic Class
- Anthelmintic
Storage Conditions
- Keep in a dry place
- Away from light and heat
- Keep out of the reach of children