Cope 25 mg (Tablet)
Unit Price: ৳ 2.50 (5 x 10: ৳ 125.00)
Strip Price: ৳ 25.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Clozapine |
| Company | Doctor tims pharmaceuticals ltd |
| Also available as |
Indications
- Schizophrenia in patients unresponsive to conventional antipsychotic drugs
- Psychosis in Parkinson's disease
Pharmacology
- Classification as an 'atypical' antipsychotic drug
- Effects on dopamine receptors
- High affinity for the D4 receptor
- Antagonist at adrenergic, cholinergic, histaminergic, and serotonergic receptors
Dosage & Administration
- Initial dose for schizophrenia in adults over 16 years
- Initial dose for psychosis in Parkinson's disease
- Maximum daily dosage
- Dosage adjustments based on response
Interaction
- Aggravated myelosuppression with concomitant myelosuppressants
- Interaction with CNS active drugs or alcohol
- Possibility of displacement by or of protein bound drugs
- Effect on plasma levels with concomitant administration of certain drugs
Contraindications
- Severe cardiac disorders
- Renal impairment
- History of neutropenia or agranulocytosis
- Bone-marrow disorders
- Alcoholic and toxic psychoses
- Uncontrolled epilepsy
- Breastfeeding
Side Effects
- Common side effects
- Less common side effects
Pregnancy & Lactation
- Inadequate studies in pregnant women
- Animal studies suggesting secretion in breast milk
- Recommendation to not nurse infants while taking the medication
Precautions & Warnings
- Importance of tapering off medication
- Monitoring for adverse effects
- Risk of agranulocytosis
- Monitoring WBC counts
- Caution in patients with seizures or impaired alertness
- Risk of hyperglycemia
- Caution in patients with hepatic disease or impairment
- Potential for orthostatic hypotension and tachycardia
- Association with myocarditis, pericarditis, and cardiomyopathy
Overdose Effects
- Signs and symptoms associated with overdose
- Management of overdose
- Specific antidotes and treatment measures
Therapeutic Class
- Atypical neuroleptic drugs
Storage Conditions
- Temperature and light restrictions
- Keep out of the reach of children