D-Proton 30 mg (Capsule (Enteric Coated))

Unit Price: ৳ 10.00 (5 x 10: ৳ 500.00)
Strip Price: ৳ 100.00

Medicine Details

Indications

  • Healing of Erosive Esophagitis
  • Maintenance of Healed Erosive Esophagitis
  • Symptomatic Non-Erosive Gastroesophageal Reflux Disease

Pharmacology

  • Proton Pump Inhibitor (PPI)
  • Suppression of gastric acid secretion
  • Specific inhibition of (H+/K+)-ATPase
  • Dual Delayed Release (DDR) formulation

Dosage

  • Dosing recommendations for dexlansoprazole
  • Different dosages for different indications
  • 30 mg once daily for maintenance of healed erosive esophagitis and relief of heartburn
  • 60 mg once daily for healing of erosive esophagitis

Administration

  • Can be taken without regard to food
  • Swallowed whole
  • Option to open capsule and sprinkle intact granules

Interaction

  • Interaction with specific medicines: Atazanavir, Warfarin, Tacrolimus, Clopidogrel & Methotrexate
  • No data available for interaction with food & others

Contraindications

  • Contraindicated in patients with known hypersensitivity

Side Effects

  • Common side effects include diarrhea, abdominal pain, nausea, vomiting & flatulence

Pregnancy & Lactation

  • Pregnancy Category B
  • No adequate and well-controlled studies in pregnant or lactating women

Precautions & Warnings

  • Gastric Malignancy
  • Clostridium difficile Associated Diarrhea
  • Bone fracture
  • Hypomagnesemia
  • Concomitant use with Methotrexate

Use in Special Populations

  • No established safety and effectiveness in patients below 12 years
  • No dose adjustment for elderly patients
  • No dose adjustment for renal impairment
  • Consider maximum daily dose for moderate hepatic impairment

Overdose Effects

  • No reports of significant overdose
  • Multiple doses of 120 mg and a single dose of 300 mg did not result in severe adverse events

Therapeutic Class

  • Proton Pump Inhibitor

Storage Conditions

  • Store below 30°C temperature
  • In a dry place protected from light
  • Keep out of reach of children

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