Fixotim 400 mg (Capsule)

Unit Price: ৳ 50.00 (2 x 7: ৳ 700.00)

Strip Price: ৳ 350.00

Medicine Details

Category	Details
Generic	Cefixime trihydrate
Company	Doctor tims pharmaceuticals ltd
Also available as	Fixotim 200 mg capsule Fixotim 100 mg suspension

Treatment of Upper Respiratory Tract Infections (URTI)
Treatment of Lower Respiratory Tract Infections
Treatment of Urinary Tract Infections
Effective against Streptococcus pneumoniae
Effective against Streptococcus pyogenes
Effective against Escherichia coli
Effective against Proteus mirabilis
Effective against Klebsiella species
Effective against Haemophilus influenzae
Treatment for infections caused by beta-lactamase positive and negative pathogens
High stability in the presence of beta-lactamase enzymes

Third generation semisynthetic cephalosporin antibiotic
Orally administered bactericidal antibiotic
Bactericidal against a broad spectrum of gram positive and gram negative bacteria
Interferes in the synthesis of bacterial cell wall
Highly stable in the presence of beta-lactamase enzyme
Approximately 40% to 50% absorption with or without food

Usual course of treatment is 7 days
Can be continued for up to 14 days if required
Recommended adult dosage is 200-400 mg daily
Elderly patients may be given the same dose as recommended for adults
Recommended dosage for children is 8 mg/kg/day
Specific daily doses in terms of volume of suspension for children of different age groups
Different dosage for typhoid in children
Dosage adjustment in severe renal impairment
Recommended dose may not be exceeded in patients with creatinine clearance less than 20 ml/min
Dosing regimen for patients on chronic ambulatory peritoneal dialysis or hemodialysis

Mostly mild and self limiting adverse reactions observed in clinical trials
Frequent gastrointestinal disturbances such as diarrhea and stool changes
Less frequent gastrointestinal side-effects including nausea, abdominal pain, dyspepsia, vomiting, and flatulence
Reported cases of pseudomembraneous colitis
Central nervous system effects like headache and dizziness
Hypersensitivity reactions in the form of rash, pruritis, urticaria, drug fever, and arthralgia
Reported cases of thrombocytopenia, leukopenia, eosinophilia, and reversible mild transient change in liver and renal function tests
Other possible reactions include genital pruritis and vaginitis

Caution required for patients with hypersensitivity to other drugs
Caution required for penicillin-sensitive patients
Caution advised for patients with markedly impaired renal function
Altered normal flora of the colon and risk of antibiotic-associated diarrhea
Not recommended for use in pregnancy or nursing mothers unless considered essential

Gastric Lavage may be indicated in case of overdose
No specific antidote exists
Not removed in significant quantities by hemodialysis or peritoneal dialysis
Adverse reactions in healthy adult volunteers receiving single doses up to 2 g did not differ from the profile seen in patients treated at recommended doses