Nok 7.5 mg (Tablet)

Unit Price: ৳ 8.00 (3 x 10: ৳ 240.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Midazolam
Company Doctor tims pharmaceuticals ltd
Also available as
Nok 15 mg tablet

Title

  • Nok - Midazolam Tablet

Categories

  • Sleep Aid
  • Premedication
  • Anxiolytic
  • Anticonvulsant
  • Muscle Relaxant

Description

  • Rapid onset sleep-inducing agent
  • Anxiolytic effect
  • Anticonvulsant effect
  • Muscle-relaxant effect

Indications

  • Short-term treatment of insomnia
  • Sedation in premedication before surgical or diagnostic procedures

Pharmacology

  • Acts through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
  • Increases activity of GABA
  • Produces sedating effect
  • Relaxes skeletal muscles
  • Induces sleep, anesthesia, and amnesia

Dosage & Administration

  • Oral dosage for adults: 7.5-15 mg daily
  • Oral dosage in elderly and debilitated patients: 7.5 mg
  • Intravenous administration for endoscopic or cardiovascular procedures
  • Intramuscular administration for adults and children
  • Rectal administration in children for preoperative sedation

Interactions

  • Enhances central sedative effect of neuroleptics, antidepressants, analgesics, antipsychotics, anxiolytics, antiepileptic drugs, and sedative antihistamines

Contraindications

  • Severe respiratory insufficiency
  • Severe hepatic insufficiency
  • Myasthenia gravis
  • Sleep apnea syndrome
  • Known hypersensitivity to benzodiazepines or any component of the product

Side Effects

  • Drowsiness during daytime
  • Confusion
  • Fatigue
  • Headache
  • Muscle weakness
  • Fluctuations in vital signs following parenteral administration
  • Respiratory depression
  • Apnea
  • Variations in blood pressure
  • Pulse rate fluctuations

Pregnancy & Lactation

  • Should be avoided during pregnancy unless no safer alternative
  • Passes into breast milk, should not be administered to breastfeeding mothers

Precautions & Warnings

  • IV administration should be very slow

Overdose Effects

  • Coma
  • Areflexia
  • Cardiorespiratory depression
  • Apnea
  • Controlled with benzodiazepine antagonist flumazenil

Therapeutic Class

  • Benzodiazepine hypnotics
  • Benzodiazepine sedatives

Storage Conditions

  • Protect from light and moisture
  • Store in a cool and dry place
  • Keep out of the reach of children

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