Pimacef 1 gm/vial (IM/IV Injection)
1 gm vial: ৳ 550.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cefepime hydrochloride |
| Company | Doctor tims pharmaceuticals ltd |
Indications
- Treatment for moderate to severe pneumonia
- Treatment for febrile neutropenia
- Treatment for uncomplicated and complicated urinary tract infections
- Treatment for uncomplicated skin and skin structure infections
- Treatment for complicated intra-abdominal infections
Pharmacology
- Bactericidal mode of action
- Disruption of peptidoglycan layer synthesis
- Functions similar to other beta-lactam antibiotics
Dosage & Administration
- Intravenous administration over approximately 30 minutes
- Specific dosages for different types of infections
- Note regarding administration route for urinary tract infections
Interaction
- Monitoring renal function during administration with aminoglycosides
- Reported nephrotoxicity with cephalosporins and diuretics
Contraindications
- Immediate hypersensitivity reactions to cefepime or cephalosporin class
Side Effects
- Immediate hypersensitivity reactions to cefepime or cephalosporin class
Pregnancy & Lactation
- Pregnancy Category B
- Excretion in very low concentrations in human breast milk
- Caution for administration to nursing women
Precautions & Warnings
- Avoiding use in absence of proven or strongly suspected bacterial infection
- Potential for overgrowth of non-susceptible microorganisms
- Association with prothrombin activity fall
- Prescribing caution for individuals with history of gastrointestinal disease
Use in Special Populations
- Pediatric use dosage limitation
- Adverse events in geriatric patients with renal insufficiency
- No adjustment necessary for impaired hepatic function
- Dose adjustment for impaired renal function
Overdose Effects
- Observation and supportive treatment for patients receiving overdose
- Recommendation of hemodialysis in the presence of renal insufficiency
- Symptoms of overdose
Therapeutic Class
- Fourth generation Cephalosporins
Reconstitution
- Administration over a period of three to five minutes
- Compatibility with different IV infusion fluids and diluents
- Specific volumes for reconstitution
Storage Conditions
- Limited use beyond expiry date
- Dispensing only on prescription of a registered physician