Tibeta 5 mg (Tablet)

Unit Price: ৳ 10.00 (3 x 10: ৳ 300.00)
Strip Price: ৳ 100.00

Medicine Details

Category Details
Generic Bisoprolol hemifumarate
Company Doctor tims pharmaceuticals ltd
Also available as
Tibeta 25 mg tablet

Indications

  • Hypertension
  • Angina
  • Moderate to severe heart failure

Pharmacology

  • Selective ß1 blocker
  • Reduces heart rate and cardiac output
  • High therapeutic reliability
  • Absorption >90%
  • Distribution volume 3.51/kg
  • Metabolized via oxidative pathways
  • Clearance of Bisoprolol is balanced between renal elimination and hepatic metabolism
  • Half-life of 10-12 hours

Dosage & Administration

  • Adult starting dose 5 mg once daily
  • Usual dose range 5-20 mg once daily
  • Dose titration interval 2 weeks
  • No established safety and effectiveness in children
  • Initial daily dose for patients with hepatic or renal impairment 5 mg
  • No adjustment required for elderly unless significant renal or hepatic dysfunction

Interaction

  • Should not be combined with other β-blocking agents
  • Catecholamine-depleting drugs may produce excessive reduction of sympathetic activity
  • β-blockers may exacerbate rebound hypertension which can follow the withdrawal of clonidine
  • Use with caution when myocardial depressants or inhibitors of A-V conduction are used concurrently
  • Combined use with calcium channel blockers with negative inotropic effects can lead to severe hypotension, bradycardia, and cardiac failure

Contraindications

  • Cardiogenic shock
  • Overt heart failure
  • Second or third degree A-V block
  • Right ventricular failure secondary to pulmonary hypertension
  • Sinus bradycardia

Side Effects

  • Fatigue
  • Dizziness
  • Headache
  • Disturbances of the gut such as nausea, vomiting, diarrhea, constipation, or abdominal pain
  • Cold or numb extremities
  • Muscle weakness or cramps
  • Breathing difficulties due to bronchospasm in people with asthma or COPD

Pregnancy & Lactation

  • Potential benefit justifies the potential risk to the fetus
  • Small amounts detected in the milk of lactating rats
  • Essential consideration and possible cessation of nursing if use is considered

Precautions & Warnings

  • Use caution in adjusting the dose in patients with renal or hepatic impairment
  • Patients with a history of severe anaphylactic reaction may be more reactive to repeated challenge

Therapeutic Class

  • Anti adrenergic agent (Beta blockers)
  • Beta-adrenoceptor blocking drugs
  • Beta-blockers

Storage Conditions

  • Keep in a dry place away from light and heat
  • Keep out of the reach of children

Chemical Structure

  • Molecular Formula : C<sub>18</sub>H<sub>31</sub>NO<sub>4</sub>

Common Questions about Tibeta 5 mg Tablet

  • Beta-blocker medication
  • Used for lowering blood pressure, reducing the workload on the heart, and preventing chest pain
  • To be taken by mouth, with or without food, once daily
  • Side effects including dizziness, fatigue, headache, slow heart rate, difficulty breathing, and cold hands and feet
  • Considerations for safe usage in cases of asthma, diabetes, heart problems, liver or kidney problems, low blood pressure, and depression
  • Should be taken after food in a prescribed dosage
  • Instructions for storage and disposal, and quick tips

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