Trixotim 1 gm/vial (IV Injection)
1 gm vial: ৳ 190.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Ceftriaxone sodium |
| Company | Doctor tims pharmaceuticals ltd |
Indications
- Lower respiratory tract infections
- Acute Bacterial Otitis Media
- Skin and skin structure infections
- Urinary tract infections
- Gonorrhea
- Bacterial Septicemia
- Bone and joint infections
- Meningitis
- Prevention of postoperative infections
- Perioperative prophylaxis of infections associated with surgery
Pharmacology
3rd generation broad-spectrum parenteral cephalosporin antibiotic
Dosage
- Adult:
- 1 to 2 gm by intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Maximum dose: 4 gm/day
- Infants and Children (01 month or older):
- 50 to 75 mg/kg intravenous or intramuscular administration once a day (or in equally divided doses twice a day)
- Usual duration is 4 to 14 days
Administration
- Intramuscular Injection:
- 250 mg or 500 mg Ceftriaxone dissolved in Lidocaine HCI 1% injection
- 1 g Ceftriaxone in 3.5 ml of Lidocaine HCI 1% injection
- Intravenous Injection:
- 250 mg or 500 mg Ceftriaxone dissolved in Water for injection
- 1 g Ceftriaxone in 10 ml of Water for injection USP
- 2 g Ceftriaxone in 20 ml of Water for injection
Interaction
No drug interactions have been reported
Contraindications
Ceftriaxone should not be given to patients with a history of hypersensitivity to cephalosporin antibiotics
Side Effects
- Gastro-intestinal effects:
- Diarrhea
- Nausea
- Vomiting
- Stomatitis
- Glossitis
- Cutaneous reactions:
- Rash
- Pruritus
- Urticaria
- Edema
- Erythema multiforme
- Hematologic reactions:
- Eosinophilia
- Thrombocytopenia
- Leucopenia
- Anemia
- Neutropenia
- Hepatic reactions:
- Elevations of SGOT or SGPT
- Bilirubinemia
- CNS reactions:
- Nervousness
- Confusion
- Sleep disturbances
- Headache
- Dizziness
- Local phlebitis: Rare following intravenous administration
Pregnancy & Lactation
Safety in human pregnancy has not been established. Low concentrations excreted in human milk.
Precautions & Warnings
- Potential for anaphylactic shock
- Anaphylactic shock requires immediate countermeasures
- Shadows suggesting sludge detected by sonograms of the gallbladder
- Blood picture should be checked at regular intervals during prolonged treatment
Use in Special Populations
Trixotim must not be given to neonates if premature and newborn (up to 28 days of age)
Overdose Effects
No specific antidote. Treatment should be symptomatic
Therapeutic Class
Third generation Cephalosporins
Storage Conditions
Vial store in a cool, dry place (below 30° C), away from light & moisture. Keep out of the reach of children