Defrol OS 2000 IU/ml (Oral Solution)
50 ml bottle: ৳ 150.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Cholecalciferol vitamin d3 |
| Company | Acme laboratories ltd |
| Also available as |
Indications
- Vitamin D3 deficiency
- Limited sunlight exposure
- Dietary deficiency
- Calcium absorption
- Phosphate absorption
- Healthy bones
- Healthy teeth
- Rickets prevention
- Osteomalacia prevention
- Osteoporosis prevention
- Pre-eclampsia prevention
- Immunity boost
Pharmacology
- Active form: Calcitriol
- Vitamin D receptors (VDRs) binding
- Calcium absorption
- Fat solubility
- Absorption in small intestine
- Metabolism in liver
- Metabolites storage
- Excretion via faeces and urine
Dosage & Administration
- Capsule dosage for adults
- Capsule dosage for children
- Film-coated tablet dosage
- Oroflash or chewable tablet dosage
- Syrup dosage
- Injection dosage
- Dosage for Vitamin D3 deficiency
- Dosage for prevention of deficiency
- Dosage for osteoporosis therapy
Interactions
- Drugs causing deficiencies
- Interference with absorption
- Magnesium containing Antacids
- Digoxin interaction
- Thiazide Diuretics interaction
- Cholestyramine interaction
- Phenytoin interaction
- Phenobarbital interaction
- Orlistat interaction
- Mineral Oil interaction
- Corticosteroids interaction
Contraindications
- Hypercalcaemia-associated diseases
- Hypersensitivity
- Toxicity evidence
Side Effects
- Anorexia
- Lassitude
- Nausea & vomiting
- Diarrhea
- Constipation
- Weight loss
- Polyuria
- Sweating
- Headache
- Thirst
- Vertigo
- Increased calcium concentration
- Increased phosphate concentration
Pregnancy & Lactation
- Safe use during pregnancy
- Recommended daily intake for pregnant women
- Excretion in breast milk
- Dose considerations for breast-fed children
Precautions & Warnings
- Plasma-calcium concentration monitoring
- Renal impairment
- Pregnancy & lactation monitoring
- Consultation for Digoxin users
- Consultation for Thiazide Diuretics users
- Consultation for liver or kidney disease patients
- Consultation for primary hyperthyroidism patients
- Consultation for lymphoma patients
- Consultation for tuberculosis patients
- Consultation for granulomatous disease patients
Use in Special Populations
- Safety & efficacy in children under 12 years
Overdose Effects
- Hypervitaminosis D
Therapeutic Class
- Bone formation
- Vitamin-D preparations
Storage Conditions
- Temperature
- Protection from light
- Protection from moisture
- Child safety