Emfolin 10 mg+5 mg (Tablet)
Unit Price: ৳ 35.00 (3 x 10: ৳ 1,050.00)
Strip Price: ৳ 350.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Empagliflozin linagliptin |
| Company | General pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibits DPP-4 enzyme
- Increases active incretin hormones
- Stimulates insulin release
- Reduces glucagon levels
- Inhibitor of Sodium-glucose co-transporter 2 (SGLT2)
Dosage & Administration
- Recommended dose: 10 mg Empagliflozin and 5 mg Linagliptin once daily
- Increased dose: 25 mg Empagliflozin and 5 mg Linagliptin once daily
- Morning intake with or without food
- Assess renal function before initiating
Interaction
- Coadministration with diuretics
- Coadministration with Insulin or Insulin secretagogues
- Effects of Rifampin on Linagliptin exposure
- SGLT2 inhibitors increase urinary glucose excretion
- Interference with 1,5-anhydroglucitol (1,5-AG) Assay
Contraindications
- Severe renal impairment
- End-stage renal disease or dialysis
- Hypersensitivity reaction to Linagliptin or Empagliflozin
Side Effects
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Genital Mycotic Infections
- Hypersensitivity Reactions
- Severe and Disabling Arthralgia
- Heart Failure
Pregnancy & Lactation
- Not recommended during the second and third trimesters of pregnancy
- Limited available data in pregnant women
Precautions & Warnings
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Urosepsis and Pyelonephritis
- Hypoglycemia
- Necrotizing Fasciitis of the Perineum
- Genital Mycotic Infections
- Heart Failure
Overdose Effects
- Contact Poison Control Center
- Supportive measures
- Clinical monitoring
- Unabsorbed material removal
- Supportive treatment
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store below 30°C temperature
- Keep away from light and wet place
- Keep out of reach of children