Glyxam 25 mg+5 mg (Tablet)
Unit Price: ৳ 50.00 (2 x 10: ৳ 1,000.00)
Strip Price: ৳ 500.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Empagliflozin linagliptin |
| Company | Popular pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Linagliptin inhibits DPP-4 enzyme
- Increases insulin biosynthesis
- Reduces glucagon secretion
- Empagliflozin inhibits SGLT2
- Reduces renal reabsorption of glucose
Dosage & Administration
- Recommended dose: 10 mg Empagliflozin and 5 mg Linagliptin once daily
- Increased dose: 25 mg Empagliflozin and 5 mg Linagliptin once daily
- Assess renal function before initiating
Interaction
- Diuretics can increase urine volume
- Increased risk of hypoglycemia with insulin
- Rifampin decreases Linagliptin exposure
Contraindications
- Severe renal impairment
- Hypersensitivity reaction to Linagliptin or Empagliflozin
Side Effects
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Hypoglycemia
- Genital Mycotic Infections
- Hypersensitivity Reactions
Pregnancy & Lactation
- Not recommended during second and third trimesters
- Limited data in pregnant women
Precautions & Warnings
- Pancreatitis
- Ketoacidosis
- Volume Depletion
- Urosepsis and Pyelonephritis
- Hypoglycemia with Insulin
- Necrotizing Fasciitis
- Genital Mycotic Infections
- Heart Failure
Overdose Effects
- Contact Poison Control Center
- Supportive measures as dictated by patient's clinical status
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store below 30°C
- Keep away from light and wet place
- Keep out of reach of children