Nervalin CR 82.5 mg (Tablet (Extended Release))
Unit Price: ৳ 25.00 (2 x 10: ৳ 500.00)
Strip Price: ৳ 250.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Pregabalin |
| Company | Beximco pharmaceuticals ltd |
| Also available as |
Title
- Nervalin CR 82.5 mg Extended-Release Tablet
Categories
- Anticonvulsant
- Analgesic
- Neurological Medication
Indications
- Neuropathic pain associated with diabetic peripheral neuropathy (DPN)
- Postherpetic neuralgia (PHN)
- Adjunctive therapy for the treatment of partial-onset seizures
- Fibromyalgia
- Neuropathic pain associated with spinal cord injury
Pharmacology
- Structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA)
- Binds with high affinity to the alpha2-delta site in central nervous system tissues
- Anti-nociceptive and antiseizure effects
Dosage
- Recommended maximum dose for diabetic peripheral neuropathy: 300 mg/day
- Recommended dose for postherpetic neuralgia: 150 to 300 mg/day
- Recommended dose for fibromyalgia: 300 to 450 mg/day
- Recommended dose for spinal cord injury: 150 to 600 mg/day
Administration
- Oral route of administration
- Pregabalin CR tablet should be swallowed whole after an evening meal
Interaction
- Unlikely to be involved in significant pharmacokinetic drug interactions
Contraindications
- Contraindicated in patients with known hypersensitivity to Pregabalin or any of its components
Side Effects
- Dizziness
- Somnolence
- Dry mouth
- Edema
- Blurred vision
- Weight gain
- Difficulty with concentration/attention
- Increased weight
- Increased appetite
Pregnancy & Lactation
- No adequate and well-controlled studies in pregnant women
- Small amounts detected in the milk of lactating women
- Not recommended during breastfeeding due to potential risk of tumorigenicity
Precautions & Warnings
- Angioedema
- Hypersensitivity reactions
- Increased risk of suicidal thoughts or behavior
- Respiratory depression
- May cause dizziness and somnolence
- Increased seizure frequency upon rapid discontinuation
- May cause peripheral edema
- Caution with concurrent use of thiazolidinedione antidiabetic agents
Use in Special Populations
- Safety and effectiveness not established in pediatric patients
Overdose Effects
- Reduced consciousness
- Depression/anxiety
- Confusional state
- Agitation
- Restlessness
- Seizures
- Heart block
- No specific antidote
Therapeutic Class
- Adjunct anti-epileptic drugs
- Primary anti-epileptic drugs
Storage Conditions
- Keep in a cool & dry place (below 30°C)
- Protected from light & moisture
- Keep out of the reach of children
Chemical Structure
- Molecular Formula: C8H17NO2
Common Questions
- First-line treatment for neurotic pain, shingles, seizures, and fibromyalgia
- Duration of usage until improvement
- Prescribed dosage
- Administration after food
- Storage and disposal instructions
- Differential effectiveness for different diseases
- Duration of intake despite feeling fine
- Possibility of using Diazepam in conjunction
- Potential weight gain
- Quick Tips