Nitro 400 mcg/spray (Topical Spray)

200 metered spray: ৳ 270.00

Medicine Details

Category Details
Generic Nitroglycerin sublingual spray
Company Unimed unihealth pharmaceuticals ltd

Indications

  • Acute relief of angina pectoris
  • Prophylaxis of angina pectoris

Description

  • Vasodilator
  • Metered dose spray

Pharmacology

  • Relaxation of vascular smooth muscle
  • Vasodilator effect on arteries and veins
  • Decreases venous return to the heart

Dosage

  • 1 or 2 metered sprays at onset of attack
  • Maximum 3 metered sprays in 15 minutes
  • Prophylactic use 5-10 minutes prior to activities

Administration

  • Important to carry at all times
  • Not for routine use
  • Special instructions for usage

Interaction

  • Severe hypotension and collapse with alcohol
  • Enhanced bioavailability of dihydroergotamine with oral nitro
  • Orthostatic hypotension with certain drug combinations

Contraindications

  • Hypersensitivity to nitrates
  • Hypotension, hypovolaemia, severe anaemia
  • Concomitant administration of phosphodiesterase inhibitors for erectile dysfunction

Side Effects

  • Headache
  • Facial flushing
  • Dizziness
  • Nausea
  • Vomiting
  • Weakness
  • Hypotension
  • Tachycardia

Pregnancy & Lactation

  • Pregnancy Category C
  • Caution when administered to nursing women

Precautions & Warnings

  • Particular attention during early days of acute myocardial infarction
  • Caution in patients with impaired renal or hepatic function, hypothyroidism

Use in Special Populations

  • Safety and effectiveness not established in pediatric patients

Overdose Effects

  • Severe hypotension
  • Throbbing headache
  • Vertigo
  • Palpitation
  • Visual disturbance
  • Flushing
  • Nausea
  • Vomiting
  • Methemoglobinemia

Therapeutic Class

  • Nitrates: Coronary vasodilators

Storage Conditions

  • Store in a cool and dry place away from light and heat
  • Keep out of the reach of children

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