Olmetor Plus 40 mg+12.5 mg (Tablet)

Unit Price: ৳ 15.00 (3 x 10: ৳ 450.00)
Strip Price: ৳ 150.00

Medicine Details

Category Details
Generic Olmesartan medoxomil hydrochlorothiazide
Company Euro pharma ltd
Also available as
Olmetor plus 20 mg tablet

Indications

  • Treatment of hypertension

Pharmacology

  • Olmesartan blocks vasoconstrictor and aldosterone-secreting effects
  • Hydrochlorothiazide is a thiazide diuretic affecting renal tubular mechanisms

Dosage & Administration

  • Usual starting dose: 20/12.5 mg
  • Dose may be titrated to 40/25 mg once daily
  • Individualized dosing

Interaction

    • Olmesartan:
      • No significant drug interactions reported
      • Not metabolized by cytochrome P450 system
    • Hydrochlorothiazide:
      • Potential interactions with alcohol, barbiturates, or narcotics
      • Possible dosage adjustment with antidiabetic drugs

Contraindications

  • Hypersensitivity to any component of the product
  • Anuria or hypersensitivity to sulfonamide-derived drugs

Side Effects

  • Common: nausea, headache, dizziness, hyperuricemia
  • Other adverse effects: chest pain, peripheral edema, diarrhea

Pregnancy & Lactation

  • Safety and effectiveness not established for nursing mothers and pregnancy
  • Discontinuation advised during these conditions

Precautions & Warnings

  • Periodic determination of serum electrolytes
  • Monitoring for potential electrolyte imbalance
  • Caution in patients with impaired renal function

Use in Special Populations

  • Usual therapy regimens for renal impairment patients with creatinine clearance >30 ml/min
  • Preferential use of loop diuretics in severe renal impairment
  • No dosage adjustment in hepatic impairment
  • Safety and effectiveness not established for pediatric patients
  • Caution in dose selection for elderly patients

Overdose Effects

  • Manifestations may include hypotension, tachycardia, electrolyte depletion
  • Supportive treatment recommended

Therapeutic Class

  • Combined antihypertensive preparations

Storage Conditions

  • Cool and dry storage
  • Protection from light and moisture
  • Keep out of reach of children

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