Emjenta 10 mg+5 mg (Tablet)

Unit Price: ৳ 35.00 (2 x 10: ৳ 700.00)
Strip Price: ৳ 350.00

Medicine Details

Category Details
Generic Empagliflozin linagliptin
Company Nipro jmi pharma ltd
Also available as
Emjenta 25 mg tablet

Indications

  • Adjunct to diet and exercise
  • Improves glycemic control
  • Type 2 diabetes mellitus

Pharmacology

  • Inhibits DPP-4 enzyme
  • Increases concentration of incretin hormones
  • Stimulates insulin release
  • Reduces glucagon levels
  • Increases urinary glucose excretion

Dosage & Administration

  • Recommended dose of 10mg Empagliflozin and 5mg Linagliptin once daily
  • Can be taken with or without food
  • Dose may be increased to 25mg Empagliflozin and 5mg Linagliptin once daily
  • Assessment of renal function before initiation
  • Discontinue if eGFR falls below 45 ml/min/1.73 m^2

Interaction

  • Coadministration with diuretics
  • Coadministration with insulin or insulin secretagogues
  • CYP3A4 inducer interaction
  • Positive urine glucose test
  • Interference with 1,5-anhydroglucitol (1,5-AG) Assay

Contraindications

  • Severe renal impairment
  • Hypersensitivity reaction to Linagliptin
  • Hypersensitivity reaction to Empagliflozin

Side Effects

  • Pancreatitis
  • Ketoacidosis
  • Volume depletion
  • Urosepsis and Pyelonephritis
  • Hypoglycemia
  • Necrotizing Fasciitis of the Perineum (Fournier's Gangrene)
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Severe and Disabling Arthralgia
  • Bullous Pemphigoid
  • Heart Failure

Pregnancy & Lactation

  • Not recommended during second and third trimesters of pregnancy
  • Limited data on use in pregnant women
  • Risks associated with poorly controlled diabetes in pregnancy

Precautions & Warnings

  • Pancreatitis
  • Hypotension
  • Ketoacidosis
  • Acute kidney injury
  • Urosepsis and Pyelonephritis
  • Hypoglycemia with Concomitant Use with Insulin & Insulin Secretagogues
  • Necrotizing Fasciitis of the Perineum (Fournier's Gangrene)
  • Genital Mycotic Infections
  • Hypersensitivity Reactions
  • Heart Failure

Overdose Effects

  • Contact Poison Control Center
  • Supportive measures
  • Removal of unabsorbed material from the gastrointestinal tract
  • Clinical monitoring
  • Supportive treatment
  • Unlikely removal by hemodialysis or peritoneal dialysis

Therapeutic Class

  • Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

Storage Conditions

  • Store below 30°C
  • Keep away from light and wet place
  • Keep out of reach of children

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