Gen HC 0.3%+1% (Ear Drop)

10 ml drop: ৳ 60.00

Medicine Details

Title

  • Gentamicin & Hydrocortisone Ear Drops and Cream

Categories

  • Otic Medication
  • Skin Medication
  • Pharmaceutical

Description

  • Treatment for chronic suppurative otitis media
  • Treatment for otitis externa
  • Prophylactic treatment for otitis externa following trauma
  • Post-operative local use in surgery to infected mastoid cavities
  • Redness, itching, and swelling of the skin

Dimensions

N/A

Color Options

  • Ear drops - colorless
  • Cream - white

Functions

  • Anti-inflammatory for skin
  • Treatment for middle ear infection
  • Treatment for ear canal infection

Materials

  • Gentamicin
  • Hydrocortisone
  • Otic solution
  • Topical cream

Technical Specifications

  • Ear Drops Dosage: 2-4 drops in affected ear 3-4 times a day
  • Cream Application: Apply to affected area of the skin 2-3 times per day

Design Elements

Ear dropper for easy application

Usability Features

  • Shake Well: Ear drops need to be shaken well immediately before use

Pharmacology

  • Gentamicin Action: Binds to ribosomal subunits disrupting protein synthesis
  • Hydrocortisone Action: Anti-inflammatory and immunosuppressive effects

Interaction

  • Gentamicin Interactions:
    • Additive effect with neurotoxic and nephrotoxic drugs
    • May potentiate the effect of anticoagulants
    • Increased risk of hypocalcaemia with bisphosphonates
  • Hydrocortisone Interactions:
    • Thiazides may enhance hyperglycemia and hypokalemia
    • Response to anticoagulants altered
    • Dose of antidiabetics and antihypertensives needs to be increased

Contraindications

  • Hypersensitivity to aminoglycoside
  • Pregnancy
  • Hepatic impairment

Side Effects

  • Allergic contact dermatitis
  • Transient irritation
  • Increased redness
  • Lacrimation

Pregnancy & Lactation

Pregnancy Category- C. Potential benefits may warrant use despite potential risks

Precautions & Warnings

  • Concurrent use of neuromuscular blocking agents
  • Conditions predisposing to ototoxicity and nephrotoxicity
  • Monitor plasma concentrations of gentamicin in certain patient groups
  • Monitor auditory and renal functions

Therapeutic Class

  • Ophthalmic steroid - antibiotic combined preparations

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