Renapine XR 50 mg (Tablet (Extended Release))

Unit Price: ৳ 8.00 (5 x 10: ৳ 400.00)
Strip Price: ৳ 80.00

Medicine Details

Category Details
Generic Quetiapine fumarate
Company Renata limited
Also available as
Renapine 100 mg tablet Renapine 25 mg tablet Renapine xr 200 mg tablet Renapine xr 300 mg tablet

Title

  • Renapine XR

Categories

  • Antipsychotic Medication
  • Pharmacotherapy
  • Neuroleptic Drugs

Description

  • Indicated for the treatment of acute and chronic psychoses, including schizophrenia
  • Belongs to the therapeutic class of atypical neuroleptic drugs
  • Administration involves dosage adjustments for different conditions
  • Caution required in concomitant use with specific medications
  • Contraindicated in patients hypersensitive to it
  • Common adverse reactions include somnolence, dizziness, and weight gain

Dimensions

  • N/A

Color Options

  • N/A

Functions

  • Treatment of acute and chronic psychoses
  • Management of manic episodes associated with bipolar disorder
  • Management of depressive episodes associated with bipolar disorder
  • Maintenance treatment of bipolar I disorder in combination with a mood stabilizer
  • Caution in concomitant use with specific medications
  • Contraindicated in hypersensitive patients

Materials

  • Quetiapine Fumarate

Technical Specifications

  • Antagonist at multiple neurotransmitter receptors in the brain
  • Antagonism of histamine H1 receptors may cause somnolence
  • Antagonism of adrenergic α receptors may cause orthostatic hypotension
  • Mechanism of action is unknown
  • No appreciable affinity at cholinergic muscarinic and benzodiazepine receptors
  • Efficacy in schizophrenia is mediated through a combination of dopamine D2 and serotonin 5HT2 antagonism

Design Elements

  • Dibenzothiazepine derivatives
  • Belongs to the chemical class of atypical psychotropic agents

Usability Features

  • Dosage should be adjusted based on clinical response and tolerability
  • Should be administered with or without food
  • Proper storage conditions should be maintained

Dosage and Administration

  • Dosage adjusted for different conditions
  • Administration frequency varies based on the condition
  • Titration required for achieving the usual effective dose range
  • Initial dose-titration period for certain conditions

Interaction

  • Caution required when used concomitantly with medicines known to cause electrolyte imbalance or to increase QT interval
  • Co-administration with specific medications increases the clearance of Renapine XR

Contraindications

  • Contraindicated in patients hypersensitive to it

Side Effects

  • Common adverse drug reactions include somnolence, dizziness, and weight gain
  • Other reported ADRs include withdrawal (discontinuation) symptoms, elevations in serum triglyceride levels, and orthostatic hypotension

Pregnancy and Lactation

  • Safety and efficacy during human pregnancy not established
  • Use during pregnancy should justify potential risks and have minimal dosage and duration
  • Degree to which it is excreted into human milk is unknown
  • Breastfeeding should be avoided while taking Quetiapine

Precautions and Warnings

  • Increased risk of suicidal thoughts, self-harm and suicide associated with depression
  • Caution in patients with known cardiovascular disease or other conditions predisposing to hypotension
  • Caution recommended when treating patients with a history of seizures
  • Consider dose reduction or discontinuation if signs of tardive dyskinesia appear
  • Neuroleptic Malignant Syndrome has been associated with antipsychotic treatment
  • Caution in patients with cardiovascular disease or family history of QT prolongation
  • Severe neutropenia uncommonly reported in Renapine XR clinical trials
  • Increases in blood glucose and hyperglycemia observed in clinical trials with Renapine XR

Use in Special Populations

  • Caution in use for the elderly
  • Not indicated for use in children and adolescents below 18 years of age

Overdose Effects

  • Survival reported in acute overdoses of up to 30 grams of Renapine XR
  • No specific antidote to Renapine XR
  • Intensive care procedures recommended for severe intoxication
  • Refractory hypotension should be treated with appropriate measures
  • Close medical supervision and monitoring recommended until recovery

Therapeutic Class

  • Atypical neuroleptic drugs

Storage Conditions

  • Store in a cool and dry place away from light
  • Do not use after the expiry date
  • Keep out of the sight and reach of children

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