Elipta 25 mg+5 mg (Tablet)
Unit Price: ৳ 40.00 (2 x 10: ৳ 800.00)
Strip Price: ৳ 400.00
Medicine Details
| Category | Details |
|---|---|
| Generic | Empagliflozin linagliptin |
| Company | Ziska pharmaceuticals ltd |
| Also available as |
Indications
- Adjunct to diet and exercise
- Improves glycemic control
- Type 2 diabetes mellitus
Pharmacology
- Inhibits DPP-4 enzyme
- Increases active incretin hormones
- Stimulates insulin release
- Decreases glucagon levels
- Regulates glucose homeostasis
- SGLT2 inhibitor
- Reduces renal reabsorption of glucose
Dosage & Administration
- Recommended dose: 10mg Empagliflozin and 5mg Linagliptin once daily
- Can be taken with or without food
- Renal function assessment before initiation
Interaction
- Increased urine volume with diuretics
- Risk of hypoglycemia with insulin or insulin secretagogues
- Potential reduction in efficacy with inducers of P-glycoprotein or CYP3A4 enzymes
- Positive urine glucose test with SGLT2 inhibitors
Contraindications
- Severe renal impairment
- Hypersensitivity reactions
- End-stage renal disease or dialysis
Side Effects
- Pancreatitis
- Ketoacidosis
- Volume depletion
- Hypoglycemia
- Genital mycotic infections
- Hypersensitivity reactions
- Heart failure
Pregnancy & Lactation
- Not recommended in second and third trimesters of pregnancy
- Limited available data in pregnant women
- Risks associated with poorly controlled diabetes in pregnancy
Precautions & Warnings
- Pancreatitis
- Hypotension
- Acute kidney injury
- Hypoglycemia
- Genital mycotic infections
- Hypersensitivity reactions
- Heart failure
Overdose Effects
- Contact Poison Control Center
- Usual supportive measures
- Clinical monitoring
- Institute supportive treatment
Therapeutic Class
- Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors
Storage Conditions
- Store below 30°C
- Keep away from light and wet place
- Keep out of reach of children